Recurrent and metastatic clivus chordoma: systemic palliative therapy retards disease progression

K Schönegger, E Gelpi, D Prayer, K Dieckmann… - Anti-cancer …, 2005 - journals.lww.com
… with progressive and metastatic clivus chordoma treated over a … quiescent intervals in recurrent
chordoma and with regression of … , while the radiotherapy was maintained to completion. …

[HTML][HTML] Sustained response of a clivus chordoma to erlotinib after imatinib failure

A Houessinon, M Boone, JM Constans… - Case Reports in …, 2015 - karger.com
… We describe a 68-year-old female in whom clivus chordoma recurred after surgery and … in
chordoma, and the third using erlotinib alone. Here, we report the longest response duration to …

Clivus chordomas: Heterogeneous tumor extension requires adapted surgical approaches

K Zweckberger, H Giese, B Haenig… - Clinical Neurology and …, 2020 - Elsevier
… our series of patients with clivus chordomas treated in our university … clivus chordoma
and status after tumor resection and C 12 radiation therapy (5 years ago). The patient suffered

Conventional external radiotherapy in the management of clivus chordomas with overt residual disease

F Zorlu, M Gürkaynak, F Yildiz, K Öge… - Neurological …, 2000 - Springer
… a clear doseresponse effect with conventional … persistent symptoms. Since all patients
in our series received more than 50 Gy (median, 60 Gy), we could not estimate a doseresponse

[HTML][HTML] A case of refractory chordoma of the clivus with a review of therapeutic targets

EI Gogo-ogute, O Alkharabsheh… - Current Problems in …, 2022 - Elsevier
… Metastasis of chordomas to the liver, lungs, bone, or soft tissues … We present a case of clival
chordoma with multiple local … , reports high levels of response rate and prolonged activity in …

[HTML][HTML] Medical treatment of advanced chordomas

V Colia, S Stacchiotti - European Journal of Cancer, 2017 - Elsevier
… On the other side, response assessment in chordoma is challenging and should incorporate
… cell-based immunotherapy combined with a sustained, stable, local release of granulocyte-…

Skull base chordomas: overview of disease, management options, and outcome

G Lanzino, AS Dumont, MBS Lopes, ER Laws - Neurosurgical focus, 2001 - thejns.org
… of the clivus can present as nasopharyngeal chordomas,16,… In recent years, continuous
refinements of frameless … with chordomas have a poorer prognosis and a poorer response to …

A transcervical transclival approach to the ventral surface of the brain stem for removal of a clivus chordoma

GC Stevenson, RJ Stoney, RK Perkins… - Journal of …, 1966 - thejns.org
… These findings were suggestive of chordoma or clival … hemiparesis; plantar responses
were bilaterally extensor. … Continuous spinal drainage was maintained by an indwelling …

[PDF][PDF] Neuroradiology case of the day. Chordoma of the clivus

EI Shoemaker, AJ Romano… - American Journal of …, 1989 - Am Roentgen Ray Soc
… On CT scans, clival chordomaschordomas. The latter tend to have shorter Ti and T2
relaxation times. Overall, chondroid … is a constant feature and may be due to obstruction …

Chordoma—current understanding and modern treatment paradigms

SM Barber, SS Sadrameli, JJ Lee, JS Fridley… - Journal of clinical …, 2021 - mdpi.com
… and respond poorly to radiotherapy and conventional chemotherapy, all of which make
chordomas … were previously thought to have a predilection for the clivus and sacrum, recent …