From circadian clock gene expression to pathologies

EW Lamont, FO James, DB Boivin, N Cermakian - Sleep medicine, 2007 - Elsevier
… these genes oscillate with a circadian rhythm. Here, we describe the regulation of clock genes
… Furthermore, we summarize the work done on human clock genes and their expression in …

Clock genes in mammalian peripheral tissues

A Balsalobre - Cell and tissue research, 2002 - Springer
… Indeed, analysis of clock gene expressions in mammals revealed that most of their … Since
these initial observations, circadian expression of clock genes was also documented in other …

Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients

G Mazzoccoli, A Panza, MR Valvano… - Chronobiology …, 2011 - Taylor & Francis
clock genes has been found in cancer patients. The aim of this study was to evaluate the
expression levels of core clock genes … ) was used to examine ARNTL1, CLOCK, PER1, PER2, …

[HTML][HTML] Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene

N Cermakian, L Monaco, MP Pando, A Dierich… - The EMBO …, 2001 - embopress.org
clock gene expression in peripheral tissues is affected, this is not the case in the SCN. Finally,
light‐induced c‐fos expression in the SCN and phase shifting of the clockclocks and/or in …

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

G Asher, D Gatfield, M Stratmann, H Reinke, C Dibner… - Cell, 2008 - cell.com
expression of several core clock genes. Moreover, we present evidence that SIRT1 binds
to CLOCK-BMAL1 heterodimers and promotes the deacetylation and degradation of PER2. …

Adrenergic regulation of clock gene expression in mouse liver

H Terazono, T Mutoh, S Yamaguchi… - Proceedings of the …, 2003 - National Acad Sciences
… nervous system entrains clock gene expression in the … gene expression in mouse liver.
Acute administration of adrenaline or noradrenaline increased mPer1 but not mPer2 expression

Dopamine receptor-mediated regulation of neuronal “clockgene expression

M Imbesi, S Yildiz, AD Arslan, R Sharma, H Manev… - Neuroscience, 2009 - Elsevier
… after quinpirole treatment in clock gene expression in vitro, we wanted to test the effect of
quinpirole on clock gene expression levels in vivo. Clock genes maintain their rhythms in …

Temporal dynamics of mouse hippocampal clock gene expression support memory processing

A Jilg, S Lesny, N Peruzki, H Schwegler… - …, 2010 - Wiley Online Library
… the clock gene mPer1, a key player implicated in both, maintenance and adaptative plasticity
of circadian clocks. … We propose that the dynamics of hippocampal clock gene expression

Clock gene expression in the murine gastrointestinal tract: endogenous rhythmicity and effects of a feeding regimen

WA Hoogerwerf, HL Hellmich, G Cornélissen… - Gastroenterology, 2007 - Elsevier
… the change in peripheral clock gene expression in response to timed feeding. In the present
study, timed feeding did not alter clock gene expression in the central clock. These findings …

Clock genes and clock-controlled genes in the regulation of metabolic rhythms

G Mazzoccoli, V Pazienza… - Chronobiology …, 2012 - Taylor & Francis
CLOCK, … CLOCK-mediated acetylation and SIRT1-mediated deacetylation of BMAL1 play
a key role in the transcriptional-translational feedback loop controlling clock gene expression. …