Use-Dependent Plasticity in Clock Neurons Regulates Sleep Need in Drosophila

JM Donlea, N Ramanan, PJ Shaw - Science, 2009 - science.org
… in mutants for Clock and cycle, both acquire LTM (6) and increase sleep after … sleep and
LTM. To further investigate the role of synaptic plasticity in clock cells, we used the Drosophila

The Drosophila Circadian Clock Gates Sleep through Time-of-Day Dependent Modulation of Sleep-Promoting Neurons

DJ Cavanaugh, AS Vigderman, T Dean, DS Garbe… - Sleep, 2016 - academic.oup.com
… of sleep-promoting neurons and show that the ability of these neurons to drive sleep varies
with … clock, implicating circadian processes. These data show that the circadian system gates …

[HTML][HTML] Circadian neuron feedback controls the Drosophila sleep–activity profile

F Guo, J Yu, HJ Jung, KC Abruzzi, W Luo, LC Griffith… - Nature, 2016 - nature.com
neurons and this feedback mechanism, the classical activity/sleep pattern of Drosophila is …
Our methods also show that these same clock neurons shape the sleep pattern in response to …

Circadian Rhythms and Sleep in Drosophila melanogaster

C Dubowy, A Sehgal - Genetics, 2017 - academic.oup.com
… of clock neurons serve different functions in allowing clocks to … signal thought to synchronize
clock neurons, although the … Secreted signals from clock neurons also influence rhythms …

Insulin signaling in clock neurons regulates sleep in Drosophila

ST Yamaguchi, J Tomita, K Kume - Biochemical and Biophysical Research …, 2022 - Elsevier
… However, the neural mechanism of sleep regulation by insulin signaling is poorly … in specific
neurons regulates sleep in Drosophila melanogaster. We analyzed the sleep behavior of …

The role of glia clocks in the regulation of sleep in Drosophila melanogaster

M Damulewicz, B Doktór, Z Baster… - Journal of …, 2022 - Soc Neuroscience
… they affect neuronal clocks. This study using Drosophila shows that oscillators in specific glia
types maintain awakeness during the day by regulating the daily plasticity of clock neurons. …

[PDF][PDF] Control of sleep-wake cycles in Drosophila

A Chatterjee, F Rouyer - A Time for Metabolism and Hormones, 2016 - library.oapen.org
… The Drosophila clock neuronal network is also remarkably simple in comparison to circadian
control circuits in vertebrates, where several brain areas, including the hypothalamus, …

Dopamine signaling in wake-promoting clock neurons is not required for the normal regulation of sleep in Drosophila

F Fernandez-Chiappe, C Hermann-Luibl… - Journal of …, 2020 - Soc Neuroscience
… and excites wake-promoting circadian clock neurons. It is therefore … clock neurons promotes
sleep, revealing a previously unappreciated complexity in the dopaminergic control of sleep

[HTML][HTML] The regulation of Drosophila sleep

OT Shafer, AC Keene - Current Biology, 2021 - cell.com
… of sleep in Drosophila, discuss their implications for understanding the fundamental functions
of sleep that … In both flies and mammals, neurons that regulate sleep and wakefulness are …

[HTML][HTML] Circadian clock neurons constantly monitor environmental temperature to set sleep timing

S Yadlapalli, C Jiang, A Bahle, P Reddy, E Meyhofer… - Nature, 2018 - nature.com
… Here we elucidate how the circadian clock neuron network of Drosophila melanogaster …
dorsal neurons 1 (DN1 p s), which are a discrete subset of sleep-promoting clock neurons 5 , …