Functional requirement for class I MHC in CNS development and plasticity

GS Huh, LM Boulanger, H Du, PA Riquelme, TM Brotz… - Science, 2000 - science.org
… In the immune system, recognition of class I MHC by T cell receptors can result in functional
… is also required for normal regressive events in the developing and adult CNS, including …

Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans

CR Blanchette, A Thackeray, PN Perrat, S Hekimi… - PLoS …, 2017 - journals.plos.org
… Our findings highlight the critical roles of heparan sulfate proteoglycans in nervous system
development and the evolutionary conservation of the molecular mechanisms driving guided …

Olig gene function in CNS development and disease

KL Ligon, SPJ Fancy, RJM Franklin, DH Rowitch - Glia, 2006 - Wiley Online Library
… Olig gene function is critical for regulation of oligodendrogenesis during embryonic and
fetal stages of CNS development. Patterning of the embryonic neural tube (left), reflected in the …

Contactins: emerging key roles in the development and function of the nervous system

Y Shimoda, K Watanabe - Cell adhesion & migration, 2009 - Taylor & Francis
… 55,Citation104–Citation107 These findings suggest that contactins might play an important
role(s) in the normal development and maintenance of central nervous system function. …

[PDF][PDF] Cytokines and CNS development

BE Deverman, PH Patterson - Neuron, 2009 - cell.com
requirements for properly regulated cytokine signaling during normal nervous system
development … stages of fetal development alter nervous system function and behavior later in life. …

CNS development: an overview

RS NOWAKOWSKI, NL HAYES - Development and psychopathology, 1999 - cambridge.org
… dramatically changed our understanding of CNS development and the relationship of ge…
of the organization of the CNS is the fact that each netics to normal and abnormal development. …

Fibroblast growth factors as regulators of central nervous system development and function

R Dono - … Journal of Physiology-Regulatory, Integrative and …, 2003 - journals.physiology.org
… In this review, I will focus on the function of FGF family members in the central nervous
system (CNS). Several Fgfs andFgfRs are expressed in the embryonic and adult CNS (Table1 …

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us

WD Snider - Cell, 1994 - Elsevier
… recently identified members of the neurotrophin family is far more complex than envisioned
on the basis of work with NGF, particularly for neurons in the central nervous system (CNS). …

Safety and regulatory requirements and challenge for CNS drug development

SC Gad - Neurobiology of Disease, 2014 - Elsevier
… disorders of the central nervous system (CNS) become more … acute, the regulatory requirements
and expectations around … Currently, these concerns and requirements are addressed …

Integrins in the development, function and dysfunction of the nervous system.

DO Clegg, KL Wingerd, ST Hikita… - Frontiers in Bioscience …, 2003 - escholarship.org
… the relevant integrin ligands that function in the nervous system. … family of receptors in the
nervous system. Since their discovery … in the development and function of the nervous system. …