… The involvement of PNNs in neuronal plasticity has been extensively studied over recent …
in neuronal development and plasticity. The PNN is an important regulator of CNS plasticity, …

… perineuronal nets (PNNs) is attracting attention as a central mechanism controlling brain
plasticity… roles as both a regulator of synaptic plasticity and a protective barrier. PNNs have a …

… is remarkably dynamic, changing its plasticity-associated conditions, including … perineuronal
nets contribute to the maturation of brain circuits and the regulation of adult brain plasticity …

… In conclusion, recent discoveries show that PNN formation contributes to a loss of brain
plasticity in adults, and that brain and spinal cord plasticity can be reestablished in adults after …

… and delineate synapses on neuronal surfaces, which led to the hypothesis that PNNs
contribute to the regulation of neuronal plasticity [22, 27]. Their function is based on the net-like …

… PNN regulation of experiencedependent cortical plasticity. In summary, PNNs function as
a critical factor that restricts CNS plasticity perhaps through several different molecular mecha…

… In conclusion, the ECM and PNNs are important regulators of CNS plasticity, both during …
the established neuronal network and reduce the plastic changes within the CNS to future …

… During development neuronal activity is required for perineuronal net expression. ►
Perineuronal net leads to decreased plasticity in adult central nervous system. ► Extracellular …

… Here, we present evidence that perineuronal nets (PNNs), a specialized extracellular …
plasticity-resistant excitatory CA2 synapses; thus, PNNs play a role in restricting synaptic plasticity …

… as neuronal proliferation and migration, and network plasticity as … the perineuronal nets
(PNNs) that surround neuronal somata… Although PNNs in the adult CNS are generally stable …