In meso structure of the cobalamin transporter, BtuB, at 1.95 Å resolution

V Cherezov, E Yamashita, W Liu, M Zhalnina… - Journal of molecular …, 2006 - Elsevier
meso structure of apo-BtuB, some of the structure changes previously noted that are caused
by the binding of cobalaminCobalamin binding causes a smaller change of order in loop 7–…

The effect of calcium on the conformation of cobalamin transporter BtuB

B Luan, R Carr, M Caffrey… - Proteins: Structure …, 2010 - Wiley Online Library
meso structure of BtuB (PDB ID: 2GUF) is similar to that of the in surfo structure; however
considerable structural … the in surfo structure were modeled according to the in meso structure. …

Native cell environment constrains loop structure in the Escherichia coli cobalamin transporter BtuB

DA Nyenhuis, TD Nilaweera, DS Cafiso - Biophysical Journal, 2020 - cell.com
… extracellular loops contribute to substrate binding and transport by the Escherichia coli
cobalamin transporter BtuB. … of BtuB, we generated predicted distances for the in meso structure ( …

Extracellular loops of BtuB facilitate transport of vitamin B12 through the outer membrane of E. coli

T Pieńko, J Trylska - PLoS Computational Biology, 2020 - journals.plos.org
… loops is crucial for cobalamin binding and transport and resembles an … of cobalamin but
also on the extension of luminal domain. We provided atomistic details of cobalamin transport

[HTML][HTML] The requirement for cobalt in vitamin B12: A paradigm for protein metalation

D Osman, A Cooke, TR Young, E Deery… - … et Biophysica Acta (BBA …, 2021 - Elsevier
… of cobalamin, a molecule called cobyric acid, requires 8 methylations, 6 amidations, extrusion
of the C20 meso … Originally thought to encode a cobalamin transporter due to sequence …

Domain alternation switches B12-dependent methionine synthase to the activation conformation

V Bandarian, KA Pattridge, BW Lennon… - Nature structural …, 2002 - nature.com
… uses bound cobalamin as an intermediate methyl carrier. … To obtain a structure displaying
the interactions of cobalamin … which 17% (w/v) meso-erythritol had been added to the reservoir …

Conformational Dynamics of the Extracellular Loop of BtuB in Whole Cells

ID Sahu - Biophysical Journal, 2020 - cell.com
… BtuB is an outer membrane transport protein of Escherichia coli … structures of ButB (ie,
surface crystal structures of ButB with calcium, calcium and cobalamin, or calcium and cobalamin

Does a Conjugation Site Affect Transport of Vitamin B12–Peptide Nucleic Acid Conjugates into Bacterial Cells?

AJ Wierzba, K Maximova, A Wincenciuk… - … A European Journal, 2018 - Wiley Online Library
… the structure of a conjugate, for example, a transporter of … transporters to various extents,
depending on the protein and the type of meso substituent (meso-imine, meso-2amine, meso-…

Vitamin B 12 and Cofactor F430

B Kräutler, BM Jaun - … of Porphyrin Chemistry: A 21st Century …, 2022 - Wiley Online Library
Vitamin B12 is the traditional specific name of the compound … side chain at C17 has acylated
meso-position C15 to give a … to a small, reduced molecule as the carrier of the reduction …

[PDF][PDF] Reconstitution of the B12 Macrocycle by Radical Ring Closure of a Blue Secocorrin

M Ruetz, SN Fedosov, B Kräutler - … Chemie International Edition, 2012 - researchgate.net
… those of vitamin B12 (1), indicating structural similarity. The … the methyl groups at the two
meso positions of cobyrinic acid … three human proteins of specific B12 transport, that is, intrinsic …