… To examine vascular risk in finer-grained detail, we conducted an exploratory study of 6
vascular/metabolic/inflammatory markers: ApoA1 (the lipoprotein for HDL cholesterol); ApoB (the …

… In conclusion, longitudinal studies now provide evidence that DM is a risk factor for cognitive
decline and dementia (AD and VaD), but the pathophysiological mechanisms underlying …

… vascular risk … cognitive decline a programme of lifestyle interventions, low fat diet, multivitamins
supplementation, regular exercise, stress reduction, and adequate control of vascular risk …

… ) found less cognitive decline, 2 found more cognitive decline, and … with a slower rate of
cognitive decline, while the other 2 … , vascular risk factors (VRF) are known to enhance the risk of …

… vascular risk scores with a dementia risk score in relation to 10-year cognitive decline in late
… has been no attempt so far to compare risk scores in predicting cognitive decline in midlife. …

… vascular risk factor exposure in midlife with progression of MRI markers of brain aging and
measures of cognitive decline… different vascular risk factors could potentially impact cognitive …

… We hypothesize that the interaction of vascular risk factor–induced cognitive decline and
the rising probability of Alzheimer pathology in the 7th and 8th decades of life increases the …

… Findings In this study, Framingham and other vascular risk algorithms were associated with
longitudinal cognitive decline, … Vascular risk maintained a strong association with cognitive …

… To determine whether vascular risk and Alzheimer disease (AD) biomarkers have independent
or synergistic effects on cognitive decline and whether vascular risk is associated with …

… We therefore hypothesize that vascular risk factors influence cognitive function by reducing
microstructural white matter integrity, in which APOE ε4 may reinforce the effect. We tested …