Sensitivity to cognitive effort mediates psychostimulant effects on a novel rodent cost/benefit decision-making task

PJ Cocker, JG Hosking, J Benoit… - …, 2012 - nature.com
… of cognitive, rather than physical, effortcognitive effort required for the potentially more
lucrative task. In human laboratory studies aimed at investigating the neurobiological basis of effort

Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work

A Westbrook, R Van Den Bosch, JI Määttä, L Hofmans… - Science, 2020 - science.org
… Moreover, catecholamine-enhancing psychostimulants alter cognitive effort in rodents (10)
and humans (16). This raises the question of whether so-called “smart drugs” act by …

Psychostimulants and cognition: a continuum of behavioral and cognitive activation

S Wood, JR Sage, T Shuman, SG Anagnostaras - Pharmacological reviews, 2014 - ASPET
… Some psychostimulants, especially at high doses and with a rapid route of … on the cognitive
effects of psychostimulants, with particular attention to low doses associated with cognitive

Nicotine increases impulsivity and decreases willingness to exert cognitive effort despite improving attention in “slacker” rats: insights into cholinergic regulation of cost …

JG Hosking, FCW Lam, CA Winstanley - PLoS One, 2014 - journals.plos.org
… Our group has recently validated a rodent Cognitive Effort Task (rCET), … cognitive effort to
earn greater rewards is a key determinant of drug response. For example, the psychostimulant

Enhancement stimulants: perceived motivational and cognitive advantages

IP Ilieva, MJ Farah - Frontiers in neuroscience, 2013 - frontiersin.org
effects. In this paper we call into question the assumption that these sizeable perceived
effects are purely cognitive. … effects of stimulants are at least as important as the cognitive

[HTML][HTML] Amphetamines improve the motivation to invest effort in Attention-Deficit/Hyperactivity Disorder

TTJ Chong, E Fortunato, MA Bellgrove - Journal of Neuroscience, 2023 - Soc Neuroscience
… preference for investing effort for reward. A, The cognitive effort task required participants to
… The physical effort task was identical to the cognitive effort task with respect to trial durations …

Cognitive effort increases the intensity of rewards

M Wahab, N Mead, S Desmercieres, V Lardeux… - bioRxiv, 2023 - biorxiv.org
… In rats, exerting a cognitive effort immediately before access to cocaine self-administration …
cognitive effort increased the psychostimulant effect of cocaine. The effects of cognitive effort

Caffeine increases psychomotor performance on the effort expenditure for rewards task

MC Wardle, MT Treadway, H de Wit - Pharmacology Biochemistry and …, 2012 - Elsevier
effort in rats. ► We tested effects of 200 mg caffeine on willingness to exert effort in humans.
… Caffeine sped performance, but did not affect willingness to exert effort. ► Stimulant …

Cognitive effort: A neuroeconomic approach

A Westbrook, TS Braver - Cognitive, Affective, & Behavioral Neuroscience, 2015 - Springer
… and neuroscientific theories of cognitive effort. Then we … than do traditional markers of cognitive
effort, including self-reports … toward understanding the cognitive and neural mechanisms …

Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning

HE Soder, JA Cooper, P Lopez-Gamundi… - …, 2021 - nature.com
… that baseline willingness to exert effort moderates the effects of stimulants on effort [29], we
… Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work. …