… The matter of white matter: Clinical and pathophysiological aspects of white matter disease
related to cognitive decline … lesions are usually separated into focal and diffuse. Almost all the …

… The white matter is an important locus for tissue damage in vascular cognitive impairment
and white matter lesions often dominate over gray matter changes. The spectrum of ischemic …

… that WMHs represent only the extreme end of a continuous spectrum of white matter injury. …
CT-visible white matter lesions that are caused by cerebral small vessel disease, as opposed …

… of cognitive impairment. To get more insight into the clinical representation of cognitive
impairment … between cognitively preserved (CP) and cognitively impaired (CI) MS patients, using …

… with Alzheimer Disease (AD) causes stroke, and when even small strokes coexist with AD,
they lower the threshold for dementia. Diffuse ischemic white matter disease impairs …

… While prior studies have shown that concomitant vascular lesions do not affect rates of
cognitive decline in those with AD, 40 results from this study suggest that the total burden and rate …

… disorders [1]. Studies that have investigated the effects of white matter lesions (WML) on
cognitive function … for brain imaging, lesion classification, and cognitive assessment and difficulty …

… White matter lesions (WMLs) play a role in cognitive decline and dementia. Little is known
about gray matter (GM) changes in WMLs. This study aimed to investigate GM changes in …

… by MRI (10, 15, 17, 24). Numerous studies focusing on MS have correlated cognitive dysfunction
with white matter disease… Cognitive deficits in both diseases are considered compatible …

… (SC) white matter lesions (WML) and cognitive function in patients with memory impairment.
… Cognitive function was assessed with the Mini-Mental State Examination (MMSE) and the …