… This study shows specific cognitive markers of neurodegeneration in REM sleep behavior
disorder (RBD) patients who will develop dementia. Attention and executive functions testing …

… z scores were used for cognitive tests according to normative data.15, 24 To assess
between-group differences in the progression of cognitive performance over prodromal years, we …

… REM sleep behavior disorder (iRBD) to identify which individuals are at greater risk of
developing a neurodegenerative disease. We confirm that cognitive … of mild cognitive impairment (…

… of overt motor, cognitive, or autonomic … prodromal features such as subjective cognitive
symptoms without evidence of impairment on neuropsychological testing, asymptomatic cognitive …

… muscle tone without history or presence of movements during REM sleep during PSG (prodromal
RBD). Moreover, SCD frequency was higher in PD-RBD patients without MCI (16 out of …

… 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting
neurologic disorder. … slowing heralds mild cognitive impairment in idiopathic REM sleep behavior …

… cognitive impairment and parkinsonism in the first years after diagnosis. Such a high risk of
disease provides an unprecedented opportunity to directly observe prodromal … and prodromal …

… prodromal synucleinopathy. We demonstrate that the pathological processes that underly
cognitive … the disease course and follow a domain-specific pattern of decline in prodromal DLB. …

… and cognition remained normal throughout the prodromal … from prodromal stages of RBD,
we have observed a prodromal … , and with normal olfaction and cognition. These findings may …

… this disease a much more sensitive and specific prodromal marker of PD, DLB, and MSA than
… glance into motor and cognitive (dream) control during REM sleep, a concept that we will …