Pharmacological strategies against cold ischemia reperfusion injury

MA Zaouali, HB Abdennebi… - Expert opinion on …, 2010 - Taylor & Francis
… The necessity of increasing the quality of organ preservation, as well as of extending cold
of cold-ischemiareperfusion (I/R) injury – and in particular cell death, mitochondrial injury and …

Ischemia-reperfusion injury: processes in pathogenetic networks: a review

H De Groot, U Rauen - Transplantation proceedings, 2007 - Elsevier
Ischemia-reperfusion injury also restricts the long-term survival of transplanted organs. …
mechanisms of ischemia-reperfusion injury, discriminating between warm and cold ischemia. We …

The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury.

M Takada, A Chandraker, KC Nadeau… - The Journal of …, 1997 - Am Soc Clin Investig
… A cold ischemia/reperfusion injury model of renal injury has been described recently (5).
Briefly, the right kidney of normal LEW rats was removed and the left kidney was isolated. The …

Role of NF-κB on liver cold ischemia-reperfusion injury

Y Takahashi, RW Ganster… - American Journal …, 2002 - journals.physiology.org
… genes, in cold ischemia-reperfusion (I/R) injury was examined after syngeneic transplantation
of liver grafts. Lewis rat recipients were killed 1–48 h after reperfusion of three different …

A mouse model of renal ischemia-reperfusion injury solely induced by cold ischemia

J Wei, Y Wang, J Zhang, L Wang, L Fu… - American Journal …, 2019 - journals.physiology.org
… with different ischemic durations. We found that the mice with <2 h of cold ischemia exhibited
no … ; animals with 3 or 4 h of cold ischemia developed into mild to moderate acute kidney …

Relevance of endoplasmic reticulum stress cell signaling in liver cold ischemia reperfusion injury

E Folch-Puy, A Panisello, J Oliva, A Lopez… - International journal of …, 2016 - mdpi.com
… In the next part of this review, we describe the relevance of the UPR/ERS changes that
occur during liver cold ischemia-reperfusion injury. We focus mainly on aspects that concern …

Natural resistance to liver cold ischemia-reperfusion injury associated with the hibernation phenotype

SL Lindell, SL Klahn, TM Piazza… - American Journal …, 2005 - journals.physiology.org
… after cold storage and were not reperfused after the ischemic … the effects of cold ischemia
followed by warm reperfusion in … not only have superior cold-storage properties compared with …

Prolonged cold ischemia in rat cardiac allografts promotes ischemiareperfusion injury and the development of graft coronary artery disease in a linear fashion

M Tanaka, GK Mokhtari, RD Terry, F Gunawan… - The Journal of heart and …, 2005 - Elsevier
… We show that ischemiareperfusion injury after prolonged cold ischemia significantly
exacerbates GCAD development in the presence of an alloimmune barrier, even 3 months after the …

Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway1

M Katori, R Buelow, B Ke, J Ma, AJ Coito, S Iyer… - …, 2002 - journals.lww.com
… In summary, our data demonstrate that HO-1 overexpression provides potent protection
against cold ischemia and reperfusion injury in a stringent rat cardiac model. This beneficial …

Prolonged cold ischemia induces necroptotic cell death in ischemiareperfusion injury and contributes to primary graft dysfunction after lung transplantation

X Wang, ME O'Brien, J Yu, C Xu, Q Zhang… - American journal of …, 2019 - atsjournals.org
Ischemiareperfusion injury (IRI) is a key event that contributes to PGD, though complex …
A one-hit model of IRI was established by inducing cold ischemia (CI) of the donor lungs at 0C …