Identification of Potential Transcriptional Biomarkers Differently Expressed in Both S. aureusand E. coliInduced Sepsis via Integrated Analysis

H Chen, Y Li, T Li, H Sun, C Tan, M Gao… - BioMed Research …, 2019 - Wiley Online Library
… Genome-wide studies identify differentially expressed genes for sepsis. However, … coli-induced
sepsis, we have analyzed four microarray datasets from GEO database and integrated

[HTML][HTML] Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria

A Mu, WP Klare, SL Baines, CN Ignatius Pang… - Nature …, 2023 - nature.com
… high-income countries severe sepsis and septic shock have a … of four sepsis-causing
pathogens: Escherichia coli, Klebsiella … Exposure to human serum generated a sepsis molecular …

Integrative “omic” analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response …

RJ Langley, JL Tipper, S Bruse, RM Baron… - … of respiratory and …, 2014 - atsjournals.org
… Escherichia coli produced mild to severe sepsis, … analysis to implicate host genomic responses
as underlying mechanisms. With this in mind, we performed a holistic integrative analysis

[HTML][HTML] Transcriptional markers classifying Escherichia coli and Staphylococcus aureus induced sepsis in adults: A data-driven approach

M Irani Shemirani - Plos one, 2024 - journals.plos.org
… Approaches such as integrated analysis for identifying prevalent genes [23], employing …
analysis [24] often yield a large number of gene lists in the output of expression analysis tools. …

[PDF][PDF] Pathogen concentration integrated molecular analysis for SMARTDIAGNOS: the next generation sepsis diagnosis

VA Chidambara, MA Shahbazi, VP Dave, TN Anh… - Infection and …, 2017 - orbit.dtu.dk
… welfare association sepsis was induced applying the model of peritoneal contamination and
infection (PCI) which lead in this case to a systemic infection dominated by Escherichia coli. …

[PDF][PDF] Research Article Identification of Potential Transcriptional Biomarkers Differently Expressed in Both S. aureus-and E. coli-Induced Sepsis via Integrated Analysis

H Chen, Y Li, T Li, H Sun, C Tan, M Gao, W Xing… - 2019 - academia.edu
… Genome-wide studies identify differentially expressed genes for sepsis. However, … coli-induced
sepsis, we have analyzed four microarray datasets from GEO database and integrated

Identification of Escherichia coli Genes That Are Specifically Expressed in a Murine Model of Septicemic Infection

MA Khan, RE Isaacson - Infection and immunity, 2002 - Am Soc Microbiol
induced in other tissues. Since chromosomal integration was not required in this procedure,
analysis of … In addition, the induction of the reporter gene can easily be detected in infected …

Early diagnosis of sepsis: is an integrated omics approach the way forward?

RJ Langley, HR Wong - Molecular diagnosis & therapy, 2017 - Springer
… The integrative analysis has highlighted the importance of mitochondrial function in
predicting patient outcomes and regulating the innate and adaptive immune response. …

An integrated microfluidic system for early detection of sepsis-inducing bacteria

YL Fang, CH Wang, YS Chen, CC Chien, FC Kuo… - Lab on a Chip, 2021 - pubs.rsc.org
… Spiked samples were further tested for the integrated microfluidic system. Whole blood
containing 10 3 CFU per mL Escherichia coli was spiked to verify the performance of the …

[HTML][HTML] Deciphering the molecular and cellular atlas of immune cells in septic patients with different bacterial infections

P Sun, M Cui, J Jing, F Kong, S Wang, L Tang… - Journal of Translational …, 2023 - Springer
coli sepsis, we performed a deconvolution analysis of a public dataset (GSE24813) from WT
… of related cells to sepsis, we analyzed cell–cell interactions in the integrated scRNA dataset. …