Phenotypic characterization of human colorectal cancer stem cells

P Dalerba, SJ Dylla, IK Park, R Liu… - Proceedings of the …, 2007 - National Acad Sciences
… of human cancer, only a phenotypic subset of cancer cellscancer cells is operationally
defined as the “cancer stem cell” … model for the study of human colorectal cancer (CRC). Solid …

DNA methylation and genetic instability in colorectal cancer cells

C Lengauer, KW Kinzler… - Proceedings of the …, 1997 - National Acad Sciences
… difference among colorectal cancer cell lines which we later tied to DNA methylation. Because
all colorectal cancer cell lines are presumably derived from the same stem cell precursor, …

[HTML][HTML] Colorectal cancer

EJ Kuipers, WM Grady, D Lieberman… - Nature reviews …, 2015 - ncbi.nlm.nih.gov
… The resected tumour specimen can be used to judge the quality of surgery; if the margin
around the specimen is free of cancer cells in both colon and rectal cancer, the surgery is …

Molecular genetics of colorectal cancer

ER Fearon - Annual Review of Pathology: Mechanisms of …, 2011 - annualreviews.org
Colorectal cancer (CRC) is a major cause of cancer morbidity and mortality. Nearly
150,000 US residents are diagnosed annually with CRC, and approximately one-third of CRC …

Extracellular matrix and colorectal cancer: how surrounding microenvironment affects cancer cell behavior?

S Crotti, M Piccoli, F Rizzolio… - Journal of cellular …, 2017 - Wiley Online Library
Colorectal cancer (CRC) whit more than a million of new cases per year is one of the most
common registered cancers worldwide with few treatment options especially for advanced …

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer

D Mouradov, C Sloggett, RN Jorissen, CG Love, S Li… - Cancer research, 2014 - AACR
… Human colorectal cancer cell lines are used … cell lines represent and maintain the genetic
diversity of primary cancers is uncertain. In this study, we profiled 70 colorectal cancer cell

Colorectal cancer

E Dekker, PJ Tanis, JLA Vleugels, PM Kasi… - The Lancet, 2019 - thelancet.com
… early detection and reduce morbidity and mortality from colorectal cancer. … cell of origin
for the majority of colorectal cancers is currently assumed to be a stem cell or stem-cell-like cell

Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

NA Dallas, L Xia, F Fan, MJ Gray, P Gaur, G Van Buren… - Cancer research, 2009 - AACR
cell lines to grow colon cancer cell spheres, or colonospheres, under serum-free conditions.
Differences between cell lines were quantitated by plating a limited number of cells in each …

Biology of colorectal cancer

MW Saif, E Chu - The Cancer Journal, 2010 - journals.lww.com
… role of colon cancer stem cells in mediating cellular drug resistance and cancer recurrence.
… adenomatous polyposis and hereditary nonpolyposis colorectal cancer, the 2 major forms of …

CD8+ T Cells Infiltrated within Cancer Cell Nests as a Prognostic Factor in Human Colorectal Cancer

Y Naito, K Saito, K Shiiba, A Ohuchi, K Saigenji… - Cancer research, 1998 - AACR
… of CD8+ T cells in 131 cases of human colorectal cancer. CD8+ T cells were classified into
… those infiltrated within cancer cell nests; (b) those distributed in the cancer stroma; and (c) …