Emerging pathways in colorectal-cancer development

AMM Haydon, JR Jass - The lancet oncology, 2002 - thelancet.com
… the emergence of new pathways in the development of colorectal cancer. There is now clear
… Instead, about 15% of colorectal cancers are characterised by microsatellite instability (MSI)…

Colorectal cancer development and advances in screening

K Simon - Clinical interventions in aging, 2016 - Taylor & Francis
… This has allowed for screening and detection of early-stage precancerous polyps before
they become cancerous in individuals at average risk for colorectal cancer (CRC), which may …

Recent developments in the treatment of metastatic colorectal cancer

JM Loree, S Kopetz - Therapeutic advances in medical …, 2017 - journals.sagepub.com
… Over the past decade there have been significant advances in the molecular characterization
of colorectal cancer (CRC) that are driving treatment decisions. Expanded RAS testing …

Role of gut microbiota in the development and treatment of colorectal cancer

C Lin, X Cai, J Zhang, W Wang, Q Sheng, H Hua… - Digestion, 1963 - karger.com
colorectal cancer (CRC). Increasing studies show that gut microbiota plays an important role
in the occurrence and development … gut microbiota and the development of CRC as well as …

[HTML][HTML] The immunogenicity of colorectal cancer in relation to tumor development and treatment

NL De Vries, M Swets, AL Vahrmeijer… - International journal of …, 2016 - mdpi.com
… In this review, we discuss the immunogenicity of colorectal cancer (CRC) in relation to tumor
development and treatment. As most tumors, CRC activates the immune system in various …

[HTML][HTML] The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
… In this review we discuss the potential role of gut microbiota in the carcinogenesis of
colorectal cancer (CRC), the possible role of bacterial metabolites in CRC development and …

[HTML][HTML] Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
… A personal history of colorectal cancer or inflammatory bowel disease (IBD)—the risk in … of
developing colorectal cancer [15]—are also important risks for colorectal cancer development,…

[HTML][HTML] Inflammatory pathways in the early steps of colorectal cancer development

F Mariani, P Sena, L Roncucci - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
… in mechanisms, like cell proliferation, DNA damage, apoptosis and autophagy, anaerobial
metabolism and tissue remodeling, considered central for colorectal cancer development. …

How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy

BA Jennings, G Willis - Cancer letters, 2015 - Elsevier
… including colorectal cancer for more than five decades. … is an increased risk of colorectal
cancer within populations. … many phenotypes, including cancer development. We describe this …

Progressing toward a molecular description of colorectal cancer development

ER Fearon, PA Jones - The FASEB journal, 1992 - Wiley Online Library
… involved in the development and progression of a common human cancer because of their
… strongly predispose to colorectal cancer. A current view is that colorectal cancer results, at …