… tumors. The natural history of colorectal tumors as a multi-step process will be considered
… of the APC gene in the development of the majority of cases of colorectal tumors has been …

… of all CRC cases, study of the molecular basis of inherited cases has greatly improved our
… CRC development. Thus, I begin this article with an in-depth description of the molecular …

… colorectal cancer development and metastasis. The Fzd7 protein is abundantly expressed in
colon cancer tissues and various colon cancer … this paper a full description of the treatment …

… is to provide an overview of the epidemiology and molecular biology of colorectal cancer and
to … that carry a markedly elevated risk of colorectal cancer. A discussion of the role of high-…

… a general overview of the different molecular … develop CRC at a younger age than the
general population, have a predilection for proximal colon cancers (70–85% of colon cancers are …

… Colorectal carcinoma remains the second most common malignancy in the … basic principles
of the molecular biology of colorectal carcinogenesis. The … Clinical description of resource. …

… development in order to recommend appropriate screening strategies. This article provides
an overview of the histological/molecular changes that characterize the development of CRC…

… A personal history of colorectal cancer or inflammatory bowel disease (IBD)—the risk in … of
developing colorectal cancer [15]—are also important risks for colorectal cancer development,…

… In particular, the study of hereditary colorectal cancer and polyposis syndromes … cancer has
contributed enormously to the understanding of the pathogenesis of CRC. Here we describe …

Colorectal cancer (CRC) has been extensively … , and describe the challenges for defining
a comprehensive, robust, and reproducible disease classification system that links molecular …