Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells

J Gong, Y Lin, H Zhang, C Liu, Z Cheng, X Yang… - Cell death & …, 2020 - nature.com
… In this study, we find that lipid metabolism reprogramming occurs in CAFs, mainly in the
increase of fatty acids, phospholipids, and glycerides. The fatty acids and phospholipids that are …

Reprogrammed lipid metabolism and the lipid-associated hallmarks of colorectal cancer

T Salita, YH Rustam, D Mouradov, OM Sieber, GE Reid - Cancers, 2022 - mdpi.com
lipid metabolism in CRC and use this growing body of evidence to propose eight lipid
metabolism-associated hallmarks of colorectal cancer, and to … to the established cancer hallmarks. …

Changes in lipids composition and metabolism in colorectal cancer: a review

A Pakiet, J Kobiela, P Stepnowski, T Sledzinski… - Lipids in health and …, 2019 - Springer
… role of many lipids in cancer cell metabolism, some of lipid metabolism pathways may … lipid
species. In this review paper, we discuss lipid alterations associated with colorectal cancer (…

Lipid metabolism as a targetable metabolic vulnerability in colorectal cancer

Y Zaytseva - Cancers, 2021 - mdpi.com
Colorectal cancer (CRC), the second leading cause of cancer-related deaths according to …
CRC and alterations in lipids [9, 10], demonstrating that lipid metabolism has a profound …

Precision nutrition for targeting lipid metabolism in colorectal cancer

C Aguirre-Portolés, LP Fernández… - Nutrients, 2017 - mdpi.com
colorectal cancer (CRC). Red and processed meat, poultry consumption, fiber, and folate are
the best-known diet components that interact with colorectal cancer … target lipid metabolism

[HTML][HTML] SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

LL Christensen, K True, MP Hamilton, MM Nielsen… - Molecular …, 2016 - Elsevier
… cell percentage of the samples in the present study was 85% for the adenomas and 75%
for the colorectal cancers indicating only minor contamination of non-tumorous cells. In …

Cancer-derived exosomal HSPC111 promotes colorectal cancer liver metastasis by reprogramming lipid metabolism in cancer-associated fibroblasts

C Zhang, XY Wang, P Zhang, TC He, JH Han… - Cell death & …, 2022 - nature.com
colorectal cancer cell line HCT116 was purchased from the China Center for Type Culture
Collection (Wuhan, China); human colorectal cancer … line, human colorectal cancer cell line …

Dysregulated lipid metabolism in colorectal cancer

O Coleman, M Ecker, D Haller - Current Opinion in …, 2022 - journals.lww.com
Lipid metabolism presents a targetable metabolic vulnerability in colorectal cancer (CRC).
Lipid signatures and cancer-cell lipid requirements may serve as noninvasive diagnostic and …

LC-MS-based lipid profile in colorectal cancer patients: TAGs are the main disturbed lipid markers of colorectal cancer progression

T Liu, F Peng, J Yu, Z Tan, T Rao, Y Chen… - Analytical and …, 2019 - Springer
… Emerging evidence has shown that lipid metabolism plays important roles in the occurrence
and progression of CRC. The identification of potential biomarkers for CRC progression is …

Colorectal cancer and metabolism

RE Brown, SP Short, CS Williams - Current colorectal cancer reports, 2018 - Springer
… Deregulated lipid metabolism is recognized as another metabolic … the lipid metabolic axis
ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role. J Lipid