Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire need
of improved prevention and treatment strategies. As our understanding of CRC grows, it is …

Original research: Depicting the landscape of gut microbial-metabolic interaction and
microbial-host immune heterogeneity in deficient and proficient DNA mismatch repair colorectal …

… in colorectal cancer, colorectal tumors are caused by genetic mutations in host DNA. Here,
we explored whether various mutations in colorectal … and the microbiome in colorectal cancer. …

… interactions are influenced by a complex metabolic environment, other microbial community
members, host mutational status, immune landscapes, and single-cell heterogeneity. In this …

… Results: We found that there is a distinct microbial distribution… positive correlations between
microbes and inflammasome … by which the colorectal cancer-associated microbiota may be …

… In the case of colorectal cancer, the analysis of mutational … Additional signatures also play
a role in colorectal cancer, … , with a focus on colorectal cancer and on the recently reported …

… of patients infected progress to cancer, suggesting that other factors other than HPV may
play a role. Some studies have investigated HPV infection in colorectal cancer (CRC) with …

… of putatively pro-carcinogenic microbial members—including … syndrome highlighted early
microbial changes in colonic … dependencies, the genetic landscape of the host could be …

… in the gut, in particular mucosally adherent microbes and microbes in the small … colorectal
cancer at an age over 80 years to be different from someone with early-onset colorectal cancer…

… Microbial dysbiosis has been hypothesized as a potential contributor, yet studies are
limited… suggests that EOCRC may have unique microbial signatures compared to both healthy …