Inhibition of apoptosis during development of colorectal cancer

A Bedi, PJ Pasricha, AJ Akhtar, JP Barber, GC Bedi… - Cancer research, 1995 - AACR
… epithelium from four discrete histopathological sources representing various stages in the
neoplastic transformation to cancer: normal mucosa, flat mucosa and adenomas from patients …

Morphometric analysis of the “mucocellular layer” overlying colorectal cancer and normal mucosa: relevance to exfoliation and stool screening

DA Ahlquist, JJ Harrington, LJ Burgart, PC Roche - Human pathology, 2000 - Elsevier
… Cellularity of the MCL was markedly and significantly higher with colorectal cancers
compared with normal mucosa based on cell number per length and cell density per cross-sectional …

[HTML][HTML] Microbial dysbiosis in colorectal cancer (CRC) patients

I Sobhani, J Tap, F Roudot-Thoraval, JP Roperch… - PloS one, 2011 - journals.plos.org
… in normal mucosa of colon Cancer patients than in Normal … both (Normal mucosa or
homologous to cancer normal mucosa) … However, IL17/CD3 ratios in normal colon mucosa

[HTML][HTML] Claudins upregulation in human colorectal cancer

SS de Oliveira, IM de Oliveira, W De Souza… - FEBS letters, 2005 - Elsevier
… In colorectal cancer tight junction molecular and morphological alterations are poorly
understood. In this study, adenocarcinoma tissues and their paired normal mucosa (n = 12) were …

Are there two sides to colorectal cancer?

B Iacopetta - International journal of cancer, 2002 - Wiley Online Library
… the study of differences between normal proximal and distal colonic mucosa, recent technical
advances open the way for a more detailed molecular profiling of colorectal cancers.35, 36 …

Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer

BB Patel, Y Yu, J Du, E Levi, PA Phillip… - Biochemical and …, 2009 - Elsevier
normal appearing colonic mucosa in patients with adenomatous polyps. More importantly,
our data show that CSC in the normal mucosa … for the age-related rise in colorectal cancer. …

Early colorectal cancer: concept, diagnosis, and management

H Kashida, S Kudo - International journal of clinical oncology, 2006 - Springer
… ,16 maintains that a cancer develops from normal mucosa through a stage of … from normal
epithelium without going through a stage of adenoma. The majority of advanced colon cancers

Natural history of colorectal cancer

SJ Winawer - The American journal of medicine, 1999 - Elsevier
… lead to rapid transformation from normal mucosa to large adenomas and to colorectal cancer.
Indeed, recurrent small and large adenomas and colorectal cancers can appear within 6 …

Mutant K‐ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis

T Minamoto, N Yamashita, A Ochiai, M Mai… - Cancer, 1995 - Wiley Online Library
… detected in apparently normal mucosa of some patients with colorectal cancer by a sensitive
… in the nonneoplastic mucosa of 14 of 70 patients (20%) with sporadic colorectal cancer, and …

[HTML][HTML] Gut microbiota signatures in tumor, para-cancerous, normal mucosa, and feces in colorectal cancer patients

Y Li, H Cao, B Fei, Q Gao, W Yi, W Han… - Frontiers in Cell and …, 2022 - frontiersin.org
… variations between tumor mucosal microbiota and normal mucosal microbiota. However, …
para-cancerous mucosal microbiota, as well as between para-cancerous and normal mucosal