… , which may benefit CRC prevention. A large body of … estrogen receptor beta (ERβ/ESR2)
demonstrates an inverse relationship with the presence of colorectal polyps and stage of tumors…

… replacement therapy, respectively, strongly suggest a protective role of estrogens on CRC …
Estrogen Receptors (ERs), estrogen receptors alpha (ER-α) and estrogen receptors beta (ER-…

… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …

… We further argue that the protective effects of estrogen are limited to … of estrogen modulators
for prevention of colorectal cancer depends on identification of susceptible colorectal cancer …

… To date, there is no evidence available showing an association between estrogen receptors
and colitis-associated cancer, but some data in murine models suggest a potential role. …

… Epidemiological data have shown that the risk of colorectal cancer is reduced among
postmenopausal hormone users, compared with those who have never used these hormones. …

… Oestrogens act via two main receptors—oestrogen receptor alpha (ERα) and oestrogen
receptor beta (ERβ), both of which are members of the nuclear receptor family [1], [16]. ERβ is …

… a possible therapeutic avenue in colorectal cancer, we report … our analysis of estrogen
signaling in the colon, including the … estrogen pathway as a therapy in colorectal cancer (CRC). …

… estrogens, while loss of expression of estrogen receptor beta has been indicated as a common
step in the development of colorectal cancer (… of estrogen receptor beta (ESR2) for cancer …

… cancer risk,implying that female hormones, namely estrogens, decrease susceptibility for
colon cancer… by which estrogens alter susceptibility for colon cancers. Coexpression of ERβ …