Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer

T Morikawa, A Kuchiba, ZR Qian… - Annals of surgical …, 2012 - Springer
colorectal cancers, we observed expansile growth pattern in 372 tumors (33%), intermediate
growth pattern in 610 tumors (… role of tumor growth pattern, utilizing a database of colorectal

IL-6 signaling promotes tumor growth in colorectal cancer

C Becker, MC Fantini, S Wirtz, A Nikolaev, HA Lehr… - Cell Cycle, 2005 - Taylor & Francis
… ing in the control of colon cancer growth. The potential relevance of our findings for human
colorectal cancer is highlighted by the finding that human colon cancer patients also show a …

Biology of colorectal cancer

MW Saif, E Chu - The Cancer Journal, 2010 - journals.lww.com
growth and proliferation of colorectal cancer. The pathways that will be discussed include
Wnt/β-catenin, TGF-β/SMAD, Notch, Hedgehog, epidermal growth … of initiating tumor growth in …

FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth

H Kaneda, T Arao, K Tanaka, D Tamura, K Aomatsu… - Cancer research, 2010 - AACR
… However, the role of FOXQ1 in humans and especially in cancer cells remains unknown.
We found that FOXQ1 mRNA is overexpressed in clinical specimens of colorectal cancer (CRC; …

The role of PDGFs and PDGFRs in colorectal cancer

RM Manzat Saplacan, L Balacescu… - Mediators of …, 2017 - Wiley Online Library
growthtumors and their expression is correlated with tumor growth and spread, therapy
resistance, and poor clinical results [5]. Understanding the role of PDGFs/PDGFRs in colorectal

[HTML][HTML] TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer

N Sheng, L Yan, K Wu, W You, J Gong, L Hu… - Cell Death & …, 2018 - nature.com
Colorectal cancer (CRC) is one of the most prevalent and fatal malignancies worldwide 1 .
In China, CRC is among the top five cancers … as an oncogene in colorectal cancer cells, but …

The interaction of platelets with colorectal cancer cells inhibits tumor growth but promotes metastasis

L Plantureux, D Mege, L Crescence, E Carminita… - Cancer Research, 2020 - AACR
… a colorectal tumor. We developed an ectopic colorectal cancer model using CT26 GFP/Luci
cancer cells… Thirty days after the injection of the cells, when the tumors reached a volume of …

Vascular endothelial growth factor in colorectal cancer

M Guba, H Seeliger, A Kleespies, KW Jauch… - … journal of colorectal …, 2004 - Springer
… To promote primary and metastatic tumor growth beyond a size independent of vascular
delivery of oxygen and nutrients, a process termed “angiogenic switch” has to be initiated by …

Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer

Y Fang, H Yu, X Liang, J Xu, X Cai - Cancer biology & therapy, 2014 - Taylor & Francis
colorectal cancer cells. Furthermore, downregulation of CCNB1 impaired colorectal cancer
proliferation in vitro and tumor growth … death in certain colorectal cancer cells. Together, these …

[HTML][HTML] MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1

D Ji, Z Chen, M Li, T Zhan, Y Yao, Z Zhang, J Xi, L Yan… - Molecular cancer, 2014 - Springer
… five colorectal cancer tissues with synchronous liver metastases and five colorectal cancer
tissues … miR-181a demonstrated overexpression in colorectal cancer with liver metastasis. …