… is expressed in human colorectal carcinoma (CRC) tissue and the extent of this expression.
… receptor has not been detected in human colorectal carcinomas (CRCs) by either molecular …

… variant expression in human colorectal mucosa [… colorectal carcinoma. Moreover, the
presence of ER-β and its variant forms may help to explain the different effects of serum estrogens …

… , estrogen molecules diffuse into cytoplasm, and bind to estrogen receptors, then modulate
gene expression … The estrogen receptor discovered in 1986 is named ERα, and another ER …

… Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …

… ERβ2 and ERβ5 were the predominant isoforms identified in 91 primary colorectal carcinoma
samples by immunohistochemistry, using custom-made antibodies raised against isoform-…

… estrogen in the prevention of colorectal cancer. We hypothesize that sometime during the
tumorigenesis process ERβ expression in colonocytes is lost and the estrogen … -to-carcinoma …

… estrogen concentration and ESR1 and ESR2 expression on CTNNB1 and CCND1 mRNA
level. As expected, expression of … Following, estrogen receptors mRNA level and estrogen …

… of four colorectal … estrogens and to interconvert E 1 and E 2 . In addition, our results suggest
for the first time that “in vitro” human colorectal cancer cells are able to metabolize estrogens …

… mechanisms for potential protective effects of estrogens on colon cancer risk. Given the
scarcity of information regarding ER mRNA expression levels in human colon, this study was …

… role for estrogens has been hypothesized. Indeed, two isoforms of nuclear estrogen receptors
(ER) have been described: ERα and ERβ. While the binding of 17beta-estradiol to ERα …