Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast

S Borrmann, P Sasi, L Mwai, M Bashraheil, A Abdallah… - PloS one, 2011 - journals.plos.org
… a significant decline of early response rates of P. falciparum infections to treatment with …
the introduction of AM-LM as first-line treatment in the Coast Province of Kenya. The parasite …

Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line …

A Sowunmi, G Ntadom, K Akano, FO Ibironke… - Infectious Diseases of …, 2019 - Springer
… -based combination therapies (ACTs). This post analyses is aimed to evaluate changes in
treatment response markers 10 years after the adoption of ACTs as first-line treatments of …

Growth rate patterns of solid tumors and their relation to responsiveness to therapy: an analytical review

SE SHACKNEY, GW McCORMACK… - Annals of internal …, 1978 - acpjournals.org
… There is an initial steeply declining segment, followed by a plateau. Advances in the treatment
… After surgery, local radiotherapy, or a combination of the two, long-term survival rates are …

Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives

DJ Angiolillo, A Fernandez-Ortiz, E Bernardo… - Journal of the American …, 2007 - jacc.org
… Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary … Clopidogrel,
in combination with aspirin, is currently the antiplatelet treatment of choice for prevention …

The PREMIER study: a multicenter, randomized, double‐blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or …

FC Breedveld, MH Weisman… - … : Official Journal of …, 2006 - Wiley Online Library
… show that there is a progressive decline in HAQ scores with time (17… responsive to either
TNF inhibition or MTX therapy, and another that mediates joint damage and is more responsive

[HTML][HTML] Combination therapy for osteoporosis: a reappraisal

F Cosman - BoneKEy Reports, 2014 - ncbi.nlm.nih.gov
… BMD did not decline at any time point during this study of TPTD/Aln combination treatment.
… Early responsiveness of women with osteoporosis to teriparatide after therapy with …

Anabolic and antiresorptive therapy for osteoporosis: combination and sequential approaches

F Cosman - Current osteoporosis reports, 2014 - Springer
… for combination treatment. This study illustrated quite clearly that the largest BMD gain with
combination treatment … Moreover, mean hip BMD did not decline at any time point during this …

Meaningful change and responsiveness in common physical performance measures in older adults

S Perera, SH Mody, RC Woodman… - Journal of the …, 2006 - Wiley Online Library
decline ranged from 0.99 to 1.88 points. For 6MWD, a small decline ranged from 21 to 54 m,
but substantial decline could not … formula to allow for the combination of these estimates, the …

Efficacy and safety of sitagliptin and metformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes

D Williams‐Herman, J Johnson, R Teng… - Diabetes, Obesity …, 2010 - Wiley Online Library
… trial and declining group … combination of sitagliptin and metformin at 104 weeks were also
similar to those observed at 54 weeks [5], suggesting durable effects on β-cell responsiveness

Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration

JJ Anderson, G Wells, AC Verhoeven… - Arthritis & Rheumatism …, 2000 - Wiley Online Library
… , 1 induction trial of a combination treatment in early RA (the … of joints would reduce
responsiveness of the swollen joint count… is a real decline in disease responsiveness with greater …