Incorporating bortezomib into the treatment of lung cancer
AM Davies, PN Lara Jr, PC Mack, DR Gandara - Clinical Cancer Research, 2007 - AACR
… cancer. In non–small cell lung cancer, bortezomib as a single agent has limited activity
but in combination with chemotherapy has shown encouraging activity without significantly …
but in combination with chemotherapy has shown encouraging activity without significantly …
Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line
MM Mortenson, MG Schlieman, S Virudachalam… - Cancer chemotherapy …, 2004 - Springer
… important when combining bortezomib with other … bortezomib was administered before the
G/C combination, there continued to be an increase in G 2 /M arrest as seen with bortezomib …
G/C combination, there continued to be an increase in G 2 /M arrest as seen with bortezomib …
Preclinical data with bortezomib in lung cancer
DP Schenkein - Clinical lung cancer, 2005 - Elsevier
… of efficacy of bortezomib to gain a full understanding of its potential in lung cancer. Preclinical
… single-agent bortezomib and bortezomib in combination with conventional chemotherapy …
… single-agent bortezomib and bortezomib in combination with conventional chemotherapy …
The potential role of bortezomib in combination with chemotherapy and radiation in non–small-cell lung cancer
MJ Edelman - Clinical lung cancer, 2005 - Elsevier
… Bortezomib has demonstrated in vitro chemotherapy- and RT–sensitizing properties as well
… activity in lung cancer. This article will review the rationale for the use of bortezomib as part …
… activity in lung cancer. This article will review the rationale for the use of bortezomib as part …
Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non–small-cell lung cancer
MP Fanucchi, FV Fossella, R Belt, R Natale… - Journal of Clinical …, 2006 - ascopubs.org
… Albanell J, Baselga J, Guix M, et al: Phase I study of bortezomib in combination with
docetaxel in anthracycline-pretreated advanced breast cancer. Proc Am Soc Clin Oncol 22::16,2003, …
docetaxel in anthracycline-pretreated advanced breast cancer. Proc Am Soc Clin Oncol 22::16,2003, …
Bortezomib-based combinations in the treatment of non–small-cell lung cancer
AM Davies, PN Lara Jr, PC Mack, PH Gumerlock… - Clinical lung cancer, 2005 - Elsevier
… This review focuses on the proteasome inhibitor bortezomib alone and in combination with
… Phase I study of bortezomib plus docetaxel in advanced non-small-cell lung cancer and …
… Phase I study of bortezomib plus docetaxel in advanced non-small-cell lung cancer and …
TRAIL therapy in non–small cell lung cancer cells: sensitization to death receptor–mediated apoptosis by proteasome inhibitor bortezomib
J Voortman, TP Resende, MAI Abou El Hassan… - Molecular cancer …, 2007 - AACR
… indicate that combination therapy of TRAIL and bortezomib may be an … combination treatment
of rhTRAIL and bortezomib, we made use of two previously established H460-derived cell …
of rhTRAIL and bortezomib, we made use of two previously established H460-derived cell …
A randomized phase II study of bortezomib and pemetrexed, in combination or alone, in patients with previously treated advanced non-small-cell lung cancer
GV Scagliotti, P Germonpré, L Bosquée… - Lung cancer, 2010 - Elsevier
… evaluate the efficacy and safety of bortezomib and pemetrexed alone or in combination, in
patients with previously treated advanced non-small-cell lung cancer (NSCLC). The primary …
patients with previously treated advanced non-small-cell lung cancer (NSCLC). The primary …
Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells
G Wu, H Li, Z Ji, X Jiang, Y Lei, M Sun - Biotechnology letters, 2014 - Springer
… non-small cell lung cancer (NSCLC) A549 and H157 cells in vitro where it inhibited cell growth
and … In addition, we also demonstrated the combined usage of bortezomib and autophagy …
and … In addition, we also demonstrated the combined usage of bortezomib and autophagy …
Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report
J Voortman, G Giaccone - BMC cancer, 2006 - Springer
… , congestive cardiac failure in a lung cancer patient who had no prior cardiac history, after
receiving an experimental treatment of bortezomib combined with chemotherapy. Elevated …
receiving an experimental treatment of bortezomib combined with chemotherapy. Elevated …
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