Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo

SH Jafri, J Glass, R Shi, S Zhang, M Prince… - … & Clinical Cancer …, 2010 - Springer
… (CDDP) is the most active chemotherapeutic agent in Lung Cancer. Here we … lung cancer
(NSCLC) and small cell lung cancer (SCLC) cell lines alone and in combination with Cisplatin (…

Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non–small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial

U Gatzemeier, A Pluzanska, A Szczesna… - Journal of Clinical …, 2007 - ascopubs.org
combined with cisplatin and gemcitabine for first-line treatment of advanced NSCLC. Overall,
the erlotinib combination … EGFR TKI gefitinib combined with platinum-based chemotherapy. …

Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer

TB de Castria, EMK da Silva… - Cochrane database of …, 2013 - cochranelibrary.com
… toxicity of carboplatin with that of cisplatin when both were combined with any third‐generation
drug. We then analysed carboplatin or cisplatin combined with each of the following drugs…

… of life in advanced non–small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: Results of an …

P Bonomi, KM Kim, D Fairclough, D Cella… - Journal of clinical …, 2000 - ascopubs.org
… The optimal dose of paclitaxel given as a 3-hour infusion in the treatment of lung cancer is
less well-defined. Phase I and II trials in which paclitaxel was combined with carboplatin have …

Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group.

S Kudoh, Y Fujiwara, Y Takada… - Journal of Clinical …, 1998 - ascopubs.org
… and small-cell lung tumor xenografts in nude mice. ,18 We previously conducted a phase I
study of the combination of CPT-11 and cisplatin for non-small-cell lung cancer (NSCLC) and …

Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells

D Minami, N Takigawa, H Takeda, M Takata… - Molecular Cancer …, 2013 - AACR
… We hypothesize that PTEN-deficient lung cancer cells suppressed … (cisplatin) and a PARP
inhibitor (olaparib). To investigate the effect of olaparib and cisplatin on PTEN-deficient lung

Randomised phase III trial of irinotecan combined with cisplatin for advanced non-small-cell lung cancer

S Negoro, N Masuda, Y Takada, T Sugiura… - … journal of cancer, 2003 - nature.com
… a standard combination chemotherapy for patients with advanced non-small-cell lung cancer
(… +cisplatin is superior to cisplatin+vindesine and that CPT-11 monotherapy is not inferior to …

Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the …

M Takada, M Fukuoka, M Kawahara… - Journal of clinical …, 2002 - ascopubs.org
cancers, 1 and it follows a more rapid clinical course than non–small-cell lung cancer. In
contrast to non–small-cell lung cancer, however, small-cell lung cancer is very sensitive to …

Phase III comparative study of high-dose cisplatin versus a combination of paclitaxel and cisplatin in patients with advanced non–small-cell lung cancer

U Gatzemeier, J von Pawel, M Gottfried… - Journal of clinical …, 2000 - ascopubs.org
lung cancer (NSCLC). Paclitaxel administered as a single agent or in combination with cisplatin
cisplatin (100 mg/m 2 ) or a combination of paclitaxel (175 mg/m 2 , 3-hour infusion) and …

Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer

VF Vasconcellos, GN Marta… - Cochrane Database …, 2020 - cochranelibrary.com
cisplatin‐based chemotherapy, both in combination with a third‐generation drug, in people
with advanced non‐small cell lung cancer (… with cisplatin and carboplatin combined with a …