The impact of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell …
… common EGFR mutations had higher response rates to EGFR-TKIs than those who had rare
EGFR mutations (… Women had increased progression-free survival (PFS) to EGFR-TKIs than …
EGFR mutations (… Women had increased progression-free survival (PFS) to EGFR-TKIs than …
Characterization of common and rare mutations in EGFR and associated clinicopathological features in a large population of Chinese patients with lung cancer
B Wei, P Ren, C Zhang, Z Wang, B Dong… - … -Research and Practice, 2017 - Elsevier
… rate of both common and rare forms of EGFR mutations and … We have found single or double
EGFR mutations in 200 (43.9… point mutations, exon 20 T790M (1.3%) and other mutations (…
EGFR mutations in 200 (43.9… point mutations, exon 20 T790M (1.3%) and other mutations (…
[HTML][HTML] Distinct epidemiology and clinical consequence of classic versus rare EGFR mutations in lung adenocarcinoma
Z Lohinai, MA Hoda, K Fabian, G Ostoros… - Journal of thoracic …, 2015 - Elsevier
… EGFR mutations responsible for primary or acquired resistance against TKI therapy. , 5 In
addition, many rare EGFR mutations (… 18–21] of EGFR excluding exon 19 microdeletions and …
addition, many rare EGFR mutations (… 18–21] of EGFR excluding exon 19 microdeletions and …
Worldwide Frequency of Commonly Detected EGFR Mutations
RP Graham, AL Treece, NI Lindeman… - … of pathology & …, 2018 - meridian.allenpress.com
… EGFR mutations are more common in southern Asia and that the distribution of activating
EGFR mutations … Sample numbers for these rare mutations were too low for statistical analysis. …
EGFR mutations … Sample numbers for these rare mutations were too low for statistical analysis. …
[HTML][HTML] Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer
… rare EGFR mutations and elaborate on the preclinical and clinical evidence for EGFRi response
for patients that harbour such rare EGFR mutations… next most common EGFR mutation in …
for patients that harbour such rare EGFR mutations… next most common EGFR mutation in …
[HTML][HTML] … responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with uncommon EGFR mutations: new insights and future …
A Russo, T Franchina, G Ricciardi, A Battaglia… - International Journal of …, 2019 - mdpi.com
… Exon 19 deletions are the most common EGFR mutations (approximately 45% of all EGFR …
The coexistence of multiple EGFR mutations is generally thought to be a relatively rare event, …
The coexistence of multiple EGFR mutations is generally thought to be a relatively rare event, …
[HTML][HTML] Uncommon EGFR Compound Mutations in Non-Small Cell Lung Cancer (NSCLC): A Systematic Review of Available Evidence
… main categories of compound EGFR mutations: combined common EGFR mutations (exon
21 p.… for the identification of increasing number of rare EGFR mutations, which often occur as …
21 p.… for the identification of increasing number of rare EGFR mutations, which often occur as …
Uncommon EGFR mutations in advanced non-small cell lung cancer
… compound mutations, defined as more than one EGFR mutation … rare genomic variants
including duplications in the EGFR … insertions, the third most common EGFR mutation, exist as a …
including duplications in the EGFR … insertions, the third most common EGFR mutation, exist as a …
A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer
HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
… (G719X or L861Q) was significantly shorter than that in those with common EGFR mutations
(2.2 versus 11.4 months; P < 0.001). That study was limited by its small sample size, as only …
(2.2 versus 11.4 months; P < 0.001). That study was limited by its small sample size, as only …
Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma
… distribution of an EGFR mutation in individual tumors is an extremely rare event. This …
Assuming the common phenomenon that EGFR is mutated throughout the tumor although …
Assuming the common phenomenon that EGFR is mutated throughout the tumor although …
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