… common EGFR mutations had higher response rates to EGFR-TKIs than those who had rare
EGFR mutations (… Women had increased progression-free survival (PFS) to EGFR-TKIs than …

… rate of both common and rare forms of EGFR mutations and … We have found single or double
EGFR mutations in 200 (43.9… point mutations, exon 20 T790M (1.3%) and other mutations (…

… EGFR mutations responsible for primary or acquired resistance against TKI therapy. , 5 In
addition, many rare EGFR mutations (… 18–21] of EGFR excluding exon 19 microdeletions and …

… EGFR mutations are more common in southern Asia and that the distribution of activating
EGFR mutations … Sample numbers for these rare mutations were too low for statistical analysis. …

… rare EGFR mutations and elaborate on the preclinical and clinical evidence for EGFRi response
for patients that harbour such rare EGFR mutations… next most common EGFR mutation in …

… Exon 19 deletions are the most common EGFR mutations (approximately 45% of all EGFR …
The coexistence of multiple EGFR mutations is generally thought to be a relatively rare event, …

… main categories of compound EGFR mutations: combined common EGFR mutations (exon
21 p.… for the identification of increasing number of rare EGFR mutations, which often occur as …

… compound mutations, defined as more than one EGFR mutation … rare genomic variants
including duplications in the EGFR … insertions, the third most common EGFR mutation, exist as a …

… (G719X or L861Q) was significantly shorter than that in those with common EGFR mutations
(2.2 versus 11.4 months; P < 0.001). That study was limited by its small sample size, as only …

… distribution of an EGFR mutation in individual tumors is an extremely rare event. This …
Assuming the common phenomenon that EGFR is mutated throughout the tumor although …