Common variation in atrial fibrillation: navigating the path from genetic association to mechanism

NR Tucker, S Clauss, PT Ellinor - Cardiovascular research, 2016 - academic.oup.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia with well-established clinical …
These advances, as well as the continued unresolved challenges for both common variation in …

[HTML][HTML] Atrial fibrillation: the role of common and rare genetic variants

MS Olesen, MW Nielsen, S Haunsø… - European Journal of …, 2014 - nature.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting 1–2% of the general
population. A number of studies have demonstrated that AF, and in particular lone AF, has a …

The role of common genetic variants in atrial fibrillation

C Paludan-Müller, JH Svendsen, MS Olesen - Journal of Electrocardiology, 2016 - Elsevier
… The reasoning for GWAS is the theory of “common variant, common disease”, proposing
that common diseases are related to variants present in more than 1–5% of the general …

Heritability of atrial fibrillation

LC Weng, SH Choi, D Klarin, JG Smith… - Circulation …, 2017 - Am Heart Assoc
… Established AF loci only explain a moderate proportion of disease risk, suggesting that further
genetic discovery, with an emphasis on common variation, is warranted to understand the …

[HTML][HTML] Variation in practice patterns among specialties in the acute management of atrial fibrillation

AM Funk, KE Kocher, JM Rohde, BT West… - BMC Cardiovascular …, 2015 - Springer
Atrial fibrillation (AF) is the most common arrhythmiaVariation regarding management
decisions such as selecting … , practice variation among physicians who commonly manage acute …

Understanding the global burden of atrial fibrillation and regional variations: we need improvement

M Vitolo, GYH Lip - Cardiovascular Research, 2021 - academic.oup.com
… , understanding the epidemiology of this common arrhythmia allows us to plan management
… of atrial fibrillation and stroke: a systematic review of the epidemiology of atrial fibrillation in …

Variations in cause and management of atrial fibrillation in a prospective registry of 15 400 emergency department patients in 46 countries: The RE-LY atrial fibrillation …

J Oldgren, JS Healey, M Ezekowitz, P Commerford… - Circulation, 2014 - Am Heart Assoc
Atrial fibrillation (AF) is the most common cardiac arrhythmia, 1 it is a leading cause of
stroke, 2 and it is associated with increased mortality. Large epidemiological studies have …

Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments

IG Stiell, CM Clement, RJ Brison, BH Rowe… - Annals of emergency …, 2011 - Elsevier
… Although recent-onset atrial fibrillation and flutter are common arrhythmias managed in the
… We seek to evaluate variation in ED management practices for recent-onset atrial fibrillation

Rare and Common Genetic Variation Underlying Atrial Fibrillation Risk

OB Vad, LM Monfort, C Paludan-Müller… - JAMA …, 2024 - jamanetwork.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia, … common and rare genetic
variation in AF risk stratification. … , 20 a common substrate in reentry arrhythmia mechanisms. We …

Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation

J Jabbari, MS Olesen, L Yuan, JB Nielsen… - Circulation …, 2015 - Am Heart Assoc
common variant A1073 is associated with increased susceptibility to AF. Both rare and
common … Hence, our study suggests that SCN10A variations are involved in the genesis of AF. …