Dual–Versus Mono–Bronchodilator Therapy in Moderate to Severe COPD: A Meta-analysis

M Lipari, PB Kale-Pradhan… - Annals of …, 2020 - journals.sagepub.com
… the magnitudecomparing dual bronchodilator therapy versus LABA monotherapy. The
mean difference in FEV 1 improvement from baseline to 12 weeks for dual bronchodilator therapy

Comparison of the bronchodilator effects of aerosol fenoterol and isoproterenol

SN Steen, R Smith, J Kuo, I Ziment, GN Beall - Chest, 1977 - Elsevier
… The bronchodilator response to isoproterenol declined in magnitude and duration during
the study period. Although the data were not statistically significant, graphic presentation of the …

Pharmacologic treatments for chronic obstructive pulmonary disease: a mixed‐treatment comparison meta‐analysis

WL Baker, EL Baker, CI Coleman - … and Drug Therapy, 2009 - Wiley Online Library
therapy was associated with the greatest positive effect on outcomes in patients with COPD.
Of the bronchodilator … with respect to both direction and magnitude. Use of MTC meta- …

Dual bronchodilation with QVA149 versus single bronchodilator therapy: the SHINE study

ED Bateman, GT Ferguson, N Barnes… - European …, 2013 - Eur Respiratory Soc
comparing LABA plus LAMA and LABA/ICS combination, improvements in lung function
achieved with two bronchodilators … this test, and reversibility of this magnitude is not unusual in …

An evaluation of single and dual long-acting bronchodilator therapy as effective interventions in maintenance therapy-naïve patients with COPD

D Singh, AD D'Urzo, JF Donohue… - … Journal of Chronic …, 2019 - Taylor & Francis
… treatment effects and treatment comparisons. LS mean differences … -naïve patients, but the
magnitude of effect of SGRQ total … intervention with dual bronchodilator therapy, as opposed to …

Bronchodilator aerosol: Comparison of administration methods

TH Smelzer, TB Barnett - JAMA, 1973 - jamanetwork.com
… The one appa¬ ratus used in these studies delivered bronchodilator to the patient via IPPB.
With a simple alteration it functioned as a powered nebulizer with the same pressure and …

Acute bronchodilator therapy does not reduce wasted ventilation during exercise in COPD

AF Elbehairy, KA Webb, P Laveneziana… - Respiratory Physiology …, 2018 - Elsevier
… In this context, bronchodilators are unlikely to modify the magnitude of stimulation of … isotime
CWR comparisons of ⩒ E /⩒CO 2 following active drug and placebo. Such comparisons are …

Clinical pharmacology of bronchodilator medications

DM Williams, BK Rubin - Respiratory Care, 2018 - rc.rcjournal.com
… on the cell surface will change the magnitude and duration of response. These changes can
be clinically relevant as they may limit the therapeutic response to treatment with prolonged …

Evaluation of bronchodilator responses in patients with “irreversible” emphysema

DE O'Donnell, L Forkert… - European Respiratory …, 2001 - Eur Respiratory Soc
… Pre- and postbronchodilator comparisons were made using … magnitude seen in the present
study group with advanced emphysema is clinically beneficial. Changes of this magnitude

Minimal clinically important differences in COPD lung function

JF Donohue - COPD: Journal of Chronic Obstructive Pulmonary …, 2005 - Taylor & Francis
… by evaluating bronchodilator reversibility by the magnitude of … In a comparison of the
bronchodilator response to albuterol … mL improvement following bronchodilator indicates …