Gemtuzumab ozogamicin

JK McGavin, CM Spencer - Drugs, 2001 - Springer
… presented for patients who achieved complete remission (CR) and complete remission
without platelet recovery (CR p ) after 2 doses of gemtuzumab ozogamicin. Pooled results from 3 …

Gemtuzumab ozogamicin: time to resurrect?

F Ravandi, EH Estey, FR Appelbaum… - Journal of Clinical …, 2012 - ascopubs.org
… approval for the use of gemtuzumab ozogamicin (GO) in … a 30% response rate (including
complete response [CR] and CR … , 61 years) with relapsed AML noted a response rate of 26%, …

Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia

J Baron, ES Wang - Expert review of clinical pharmacology, 2018 - Taylor & Francis
… The results failed to show any improvement in complete response rate, RFS, or OS rates
when GO was added. Moreover, a significantly higher mortality rate of 5.5% was reported in the …

Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from …

RK Hills, S Castaigne, FR Appelbaum… - The lancet …, 2014 - thelancet.com
… of gemtuzumab ozogamicin did not increase the proportion of patients achieving complete
remission with or without complete … However, the addition of gemtuzumab ozogamicin

[HTML][HTML] Gemtuzumab ozogamicin: back again

C Selby, LR Yacko, AE Glode - Journal of the Advanced …, 2019 - ncbi.nlm.nih.gov
… demonstrated complete response (CR) or complete response … approval process, gemtuzumab
ozogamicin was allowed … that phase III studies be completed as planned to prove benefit …

Outcomes in patients treated with gemtuzumab ozogamicin for relapsed acute myelogenous leukemia

K Lang, J Menzin, CC Earle… - American journal of health …, 2002 - academic.oup.com
… Duration of second complete remission in patients with acute myeloid leukemia treated
with chemotherapy: a retrospective single-center study. Ann Hematol. 1996; 72:216-22. …

[HTML][HTML] Gemtuzumab ozogamicin for de novo acute myeloid leukemia: final efficacy and safety updates from the open-label, phase III ALFA-0701 trial

J Lambert, C Pautas, C Terré, E Raffoux, P Turlure… - …, 2019 - ncbi.nlm.nih.gov
… Patients with a complete remission (CR) or CR with incomplete platelet recovery (CRp)
after induction treatment received 2 courses of consolidation, including DNR and AraC with or …

Gemtuzumab ozogamicin in combination with intensive chemotherapy in relapsed or refractory acute myeloid leukemia

SP Chantepie, E Reboursiere, JB Mear… - Leukemia & …, 2015 - Taylor & Francis
… The complete response (CR) rate after relapse is around 25%, with 11% of patients still
alive after 5 years. The efficacy and toxicity of fractionated gemtuzumab ozogamicin (fGO; 3 mg/…

Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia

PF Bross, J Beitz, G Chen, XH Chen, E Duffy… - Clinical cancer …, 2001 - AACR
… The complete response (CR) rate with full recovery of hematopoiesis was 16%. A subset
of patients [CRs with incomplete platelet recovery (CRps)] was identified with blast clearance …

Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse

…, FR Appelbaum, Mylotarg Study Group - Journal of Clinical …, 2001 - ascopubs.org
… CONCLUSION: Administration of the antibody-targeted chemotherapy agent Mylotarg to
patients with CD33-positive AML in first relapse induces complete remissions with what appears …