Nitric oxide synthase and cyclooxygenase pathways: a complex interplay in cellular signaling
A Sorokin - Current Medicinal Chemistry, 2016 - ingentaconnect.com
… a molecule of the year, the first reports of interplay of PGs signaling and release of NO have
… the complex interplay of signal transduction pathways. This review will discuss the interplay …
… the complex interplay of signal transduction pathways. This review will discuss the interplay …
Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition
LS Premkumar, M Raisinghani - Molecular Pain, 2006 - journals.sagepub.com
Prostaglandins (PGs) are requisite components of inflammatory pain as indicated by the
efficacy of cyclooxygenase 1/2 (COX1/2) inhibitors. PGs do not activate nociceptive ion …
efficacy of cyclooxygenase 1/2 (COX1/2) inhibitors. PGs do not activate nociceptive ion …
Interplay between oxidative stress, cyclooxygenases, and prostanoids in cardiovascular diseases
… Critical Issues: Comprehensive understanding of the complex interplay between oxidative
stress, COXs, and prostanoids in CVDs helps develop more effective measures against …
stress, COXs, and prostanoids in CVDs helps develop more effective measures against …
Interplay between cyclooxygenase‑2 and microRNAs in cancer
Z Gong, W Huang, B Wang… - Molecular …, 2021 - spandidos-publications.com
Tumor‑associated inflammation and aberrantly expressed biomarkers have been demonstrated
to play crucial roles in the cancer microenvironment. Cyclooxygenase‑2 (COX‑2), a …
to play crucial roles in the cancer microenvironment. Cyclooxygenase‑2 (COX‑2), a …
Heme oxygenase and cyclooxygenase in the central nervous system: a functional interplay
C Mancuso, M Perluigi, C Cini… - Journal of …, 2006 - Wiley Online Library
Heme oxygenase (HO) and cyclooxygenase (COX) are two hemeproteins involved in the
regulation of several functions in the nervous system. Heme oxygenase is the enzyme …
regulation of several functions in the nervous system. Heme oxygenase is the enzyme …
Competition and allostery govern substrate selectivity of cyclooxygenase-2
MM Mitchener, DJ Hermanson… - Proceedings of the …, 2015 - National Acad Sciences
… -2 might result in a complex interplay between the substrates … the multiple reaction pathways
that exist between the two … formation of multiple complexes via a variety of pathways. A more …
that exist between the two … formation of multiple complexes via a variety of pathways. A more …
Transcriptional regulation of cyclooxygenase-2 in response to proteasome inhibitors involves reactive oxygen species-mediated signaling pathway and recruitment of …
JJ Chen, WC Huang, CC Chen - Molecular biology of the cell, 2005 - Am Soc Cell Biol
Inhibition of ubiquitin-proteasome pathway has been shown to be a promising strategy for
the treatment of inflammation and cancer. Here, we show that proteasome inhibitors MG132, …
the treatment of inflammation and cancer. Here, we show that proteasome inhibitors MG132, …
Complexity of COX-2 gene regulation
KA Harper, AJ Tyson-Capper - Biochemical Society transactions, 2008 - portlandpress.com
… 2 gene involves cross-talk between multiple signalling pathways depending on cell type and
stimulus. RNA-processing events involving a complex interplay of specific trans-acting RNA-…
stimulus. RNA-processing events involving a complex interplay of specific trans-acting RNA-…
Cyclooxygenase 2: its regulation, role and impact in airway inflammation
NN Rumzhum, AJ Ammit - Clinical & Experimental Allergy, 2016 - Wiley Online Library
… via two independent pathways 36, 37. The first degradative pathway is called substrate-induced …
By examining the complex interplay between eicosanoids, we have achieved more than …
By examining the complex interplay between eicosanoids, we have achieved more than …
Nitric oxide signaling and the cross talk with prostanoids pathways in vascular system
BR Silva, TD Paula, M Paulo… - Medicinal …, 2017 - ingentaconnect.com
… Moreover, the enzyme cyclooxygenase (COX) is also an … effects of ruthenium-derived
complexes that release NO. Our … and COX suggests that the interplay could involve other cellular …
complexes that release NO. Our … and COX suggests that the interplay could involve other cellular …