… , pancreatic cancer (PaCa) cells are confronted with nutrient deprivation and hypoxia. Here,
we investigate the roles of autophagy and metabolism … the metabolic profile, as it was difficult …

… and tumor cell interactions with its complex stroma. We present a comprehensive overview
of the main metabolic … Taken together, this suggests that pancreatic tumor cells adapt to …

… remodeling and maturation of tumor vasculature [51], forming a complex with angiopoietins
and … clarified key aspects of the metabolic signature of pancreatic cancer stem cells (PCSCs) …

… Therefore, metabolic alteration of pancreatic cancer is a … of pancreatic cancer cells [32],
there is a complex and harsh … The landscape of metabolic pathways in pancreatic cancer …

… when identifying myCAFs in pancreatic cancer, different model-… [25] explored the CAF
landscape of pancreatic tumors in KPP … However, cancer cell metabolism is far more complex than …

… Altered glycolysis has been recognized as the major metabolic alteration in pancreatic
cancer. The glycolytic flux in cancers is tightly controlled to meet the fast proliferative needs, as …

… Deep insight has been gained regarding the metabolic and immunological deregulation,
which further sheds light on the complex biology and the observed treatment recalcitrance. …

… The heterogeneous genomic landscape of pancreatic tumours may converge on a common
… types are not fully established, and are likely complex given the highly integrated nature of …

… trials target pro-tumorigenic metabolic pathways, either as stand-… future directions of pancreatic
cancer metabolism research, … progression on cholesterol is, however, more complex than …

… pancreatic cancer subtypes each display distinctive aberrations in cell signaling and metabolic
… by inhibiting the pyruvate dehydrogenase complex in cancers of the breast and kidney [29…