Genetic toxicity of complex mixtures of polycyclic aromatic hydrocarbons: evaluating dose-additivity in a transgenic mouse model
AS Long, CL Lemieux, R Gagné… - … science & technology, 2017 - ACS Publications
… the complex mixtures studied, we compared the complex mixture results to results obtained
with synthetic mixtures only … Additionally, in order to examine the PEF-M for PAH mixtures, we …
with synthetic mixtures only … Additionally, in order to examine the PEF-M for PAH mixtures, we …
Mixture toxicity and gene inductions: can we predict the outcome?
F Dardenne, I Nobels, W De Coen… - … and Chemistry: An …, 2008 - Wiley Online Library
… Mixture toxicity is a complex issue and remains poorly understood. This is illustrated … Mixture
toxicity can be influenced by different interactions of the compounds composing the mixture …
toxicity can be influenced by different interactions of the compounds composing the mixture …
Utility of short-term tests for genetic toxicity
DM DeMarini, J Lewtas, HE Brockman - Cell biology and toxicology, 1989 - Springer
… By definition, short-term tests (STTs) for genetic toxicity detect genotoxic agents, … complex
mixtures as well as the antimutagenic effects of various pure compounds and complex mixtures…
mixtures as well as the antimutagenic effects of various pure compounds and complex mixtures…
Genetic toxicity of a mixture of fifteen pesticides commonly found in the Italian diet
P Dolara, A Vezzani, G Caderni, C Coppi… - Cell biology and …, 1993 - Springer
… To determine the toxicological effects of complex mixtures of pesticides, we obtained data
on 100 pesticide residues in common foods of central Italy. Fifteen pesticides were more …
on 100 pesticide residues in common foods of central Italy. Fifteen pesticides were more …
A Panel of Quantitative Calux® Reporter Gene Assays for Reliable High‐Throughput Toxicity Screening of Chemicals and Complex Mixtures
B van der Burg, S van der Linden… - … methods in toxicity …, 2013 - Wiley Online Library
… of toxicity of new chemicals and pharmaceuticals, either alone or in complex mixtures as …
used chemicals alone, not to speak of the complex mixtures we are exposed to. A major reason …
used chemicals alone, not to speak of the complex mixtures we are exposed to. A major reason …
The genotoxicity of priority polycyclic aromatic hydrocarbons in complex mixtures
PA White - … Research/Genetic Toxicology and Environmental …, 2002 - Elsevier
… ) substances in complex mixtures. Lack of information about the behavior of toxic substances
in complex mixtures is often avoided by assuming that the toxicity of a mixture is simply the …
in complex mixtures is often avoided by assuming that the toxicity of a mixture is simply the …
Modeling the toxicity of pollutants mixtures for risk assessment: a review
M Sigurnjak Bureš, M Cvetnić, M Miloloža… - Environmental chemistry …, 2021 - Springer
… numerical methods such as genetic algorithm, neural networks, … mixture toxicity and clarify
the interaction between mixture components. The risk assessment of mixtures is a complex …
the interaction between mixture components. The risk assessment of mixtures is a complex …
Environmental complex mixture toxicity assessment.
HS Gardner Jr, LM Brennan… - Environmental …, 1998 - ehp.niehs.nih.gov
… characterized as a mixture scenario. The use of bioassays to assess mixtures of complex
environmental chemical contaminants has involved both in vitro genetic toxicity assays as well …
environmental chemical contaminants has involved both in vitro genetic toxicity assays as well …
Complex mixtures: Methods for in vivo toxicity testing
, … for the In Vivo Toxicity Testing of Complex Mixtures - 1988 - books.google.com
… the toxicity of simple mixtures, particularly binary mixtures. … in permitting the extrapolation of
toxicity to lower doses. Although … in assessing the toxicity of more complex mixtures, it is clear …
toxicity to lower doses. Although … in assessing the toxicity of more complex mixtures, it is clear …
[PDF][PDF] Environmental toxicity of complex chemical mixtures
AM Gillespie - 2010 - core.ac.uk
… A variety of technologies, including molecular biology, chemistry, and genetics have …
complex mixture toxicity. Studies were conducted to measure the genotoxicity of complex mixtures …
complex mixture toxicity. Studies were conducted to measure the genotoxicity of complex mixtures …
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