… Once we get to really complex signaling networks such as those involved in cell fate
decisions, the modular approach becomes difficult to use. First, it may be difficult to find a clean …

… between natural signaling networks and man-made networks. … signaling networks from a
more theoretical point of view. Thus, rather than building numerical models of complex networks…

… The inherent complexity of cellular signaling networks and their importance to a wide range
… predictions for complex cellular signaling networks. A key difficulty with signaling models is …

… The cell appears to use these complex networks of interacting pathways and regulatory …
the ‘‘systems behavior’’ of signaling networks. Rather it has become necessary to devel- …

… We applied the algorithm to the signaling networks of E. coli, S. cerevisiae, and H. sapiens,
where we define the signaling network as an integrated network of all the signaling pathways …

… Emergence of complex dynamics in simple signaling networks. (a) The units constituting
the network, which are located on the nodes of a one-dimensional lattice, have bidirectional …

… such complex programs [2]. The field of adhesion has become formidably complex because
of … of function that might indicate the role that adhesion molecules play in signaling networks. …

… to enhance the utility of logic-based methods for studying the relationship between
environmental inputs and phenotypic or signaling state outputs of complex signaling networks. …

… signaling networks is the formation of complexes of signaling proteins. The organization of
these complexes is dynamic and the complexes … the best described of these complexes is the …

… We believe that the possibility of in-silico execution of putative models is an efficient way to
help biologists understand the behavior of a complex signaling networks. Counter example …