… In summary, compound EGFR mutations comprised 14% of all mutations identified during …
18 to 21 of EGFR in our cohort. Most tumors with an EGFR sensitizing mutation (G719X, exon …

… actionable oncogenic mutations. This study shows that the compound EGFR mutation is
common in lung adenocarcinoma and imparts a new meaning of compound EGFR mutation. …

… the issue of the distribution of compound EGFR mutations. For this purpose, according to …
main categories of compound EGFR mutations: combined common EGFR mutations (exon 21 p.…

… We divided the cohort with the compound EGFR mutations into … mutations sites reported
in the literature: a double common mutation group (5/106, 4.7%), a common plus rare mutation …

… with compound EGFR mutations. We compared compound EGFR mutations with
common or uncommon single-mutation cases. Our study expands the comprehension of the …

… The most classic mutations have been well investigated, while few studies have focused on
… EGFR mutations such as compound EGFR mutations where two or even more mutations …

… EGFR mutations and their sensitivity to EGFR-TKIs. Favorable responses were observed in
patients with G719X and compound L858R mutations, … of compound EGFR mutations in this …

… cis compound EGFR mutation and single EGFR L858R. We randomly selected 23 patients
from our screened cohort harboring single EGFR … with in cis compound EGFR mutation. The …

… lung adenocarcinoma harboring compound uncommon EGFR mutations, G719X in exon 18
… efficacy of EGFR-TKIs in lung cancers harboring rare compound EGFR mutations cannot be …

… uncommon EGFR mutations (single or compound mutation). Patients were treated with EGFR…
Median OS resulted longer in the compound mutation group when compared to single rare …