[HTML][HTML] Addiction-like reward dysfunction and compulsive eating in obese rats: Role for dopamine D2 receptors

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - ncbi.nlm.nih.gov
… for reward hyposensitivity 6 . Importantly, it is presently unclear if deficits in reward
food is sufficient to drive reward dysfunction and thereby contribute to diet-induced obesity. …

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - nature.com
… for reward hyposensitivity 6 . Notably, it is unclear whether deficits in reward processing are
… palatable food can drive reward dysfunction and thereby contribute to diet-induced obesity. …

Reward sensitivity deficits in a rat model of compulsive eating behavior

CF Moore, MZ Leonard, NM Micovic… - …, 2020 - nature.com
… behavior is hypothesized to be driven in part by rewardreward system functioning and
mesolimbic DA after alternating a standard chow with palatable diet, a model of compulsive eating

The dark side of compulsive eating and food addiction: Affective dysregulation, negative reinforcement, and negative urgency

EP Zorrilla, GF Koob - Compulsive eating behavior and food addiction, 2019 - Elsevier
… proposes that overconsumption of palatable food downregulates mesolimbic dopaminergic
reward circuitry, a within-system opponent-process adaptation. Mechanisms, similar to those …

Neuropharmacology of compulsive eating

CF Moore, JI Panciera, V Sabino… - … Transactions of the …, 2018 - royalsocietypublishing.org
compulsive eating behaviour can be broadly mapped to dysfunctions of three key brain regions
involving reward … and kappa- opioid system dysfunction in the PFC in compulsive eating, …

Corrigendum: Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats.

PM Johnson, PJ Kenny - 2010 - psycnet.apa.org
… development of addiction-like reward deficits and the onset of compulsive-like food seeking
… in brain reward circuits and drives the development of compulsive eating. Common hedonic …

[HTML][HTML] The cognitive drivers of compulsive eating behavior

N Kakoschke, E Aarts, A Verdejo-García - Frontiers in behavioral …, 2019 - frontiersin.org
… of obsessive-compulsive and addictive disorders, … eating in terms of repetitive behavior
despite negative consequences. Excessive eating behavior is characteristic of several eating-…

Reward circuit function in high BMI individuals with compulsive overeating: similarities with addiction

FM Filbey, US Myers, S DeWitt - Neuroimage, 2012 - Elsevier
compulsive overeating (eating uncontrollably even when not physically hungry, commonly
referred to as “binge eating”) … , and further support the role of dopamine in this dysfunction. …

[HTML][HTML] Pathological overeating: emerging evidence for a compulsivity construct

CF Moore, V Sabino, GF Koob, P Cottone - Neuropsychopharmacology, 2017 - nature.com
… result in compulsive eating behaviors. Here, we present evidence to relate compulsive eating
… elements emerge from dysfunctions of brain areas involved in reward learning, emotional …

Target identification and validation in brain reward dysfunction

LF Alguacil, C González-Martín - Drug Discovery Today, 2015 - Elsevier
… for treating compulsive eating and several … reward disorders potentially involved in eating
disorders and obesity. Various experimental manipulations can precipitate compulsive eating