Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2
K Al-Khafaji, D Al-Duhaidahawi… - Journal of Biomolecular …, 2021 - Taylor & Francis
… As a result of, a newly issued X-ray crystal of SARS-CoV-2 Main protein (Mpro), we planning
to use computational approaches (Cameron et al., 2013) to contribute to find an effective …
to use computational approaches (Cameron et al., 2013) to contribute to find an effective …
Progress in computational approach to drug development against SARS
… polyproteins by a special proteinase, the so-called SARS coronavirus main proteinase (SARS
CoV Mpro), is a key step for the replication of the “culprit”. The functional importance of the …
CoV Mpro), is a key step for the replication of the “culprit”. The functional importance of the …
Drug repurposing against SARS-CoV-2 using computational approaches
… by the computational approaches. Among the hits identified by computational approaches,
35 … ten drugs are in clinical trials (Phase III and IV) for treating Coronavirus 2019 (COVID-19). …
35 … ten drugs are in clinical trials (Phase III and IV) for treating Coronavirus 2019 (COVID-19). …
Knowing and combating the enemy: a brief review on SARS-CoV-2 and computational approaches applied to the discovery of drug candidates
MSM Serafim, JC Gertrudes, DMA Costa… - Bioscience …, 2021 - portlandpress.com
… (CADD) approaches, … SARS-CoV-2. In this work, we describe and review the current
knowledge on this virus and the pandemic, the latest strategies and computational approaches …
knowledge on this virus and the pandemic, the latest strategies and computational approaches …
Identification of chymotrypsin-like protease inhibitors of SARS-CoV-2 via integrated computational approach
… has been approved for clinical testing against novel coronavirus. It has been found to be …
the emerging infection of SARS-CoV-2. In this study, we used an approach for target based-…
the emerging infection of SARS-CoV-2. In this study, we used an approach for target based-…
A computational approach to identify potential novel inhibitors against the coronavirus SARS‐CoV‐2
V Battisti, O Wieder, A Garon, T Seidel… - Molecular …, 2020 - Wiley Online Library
… a potential new multi-target SARS-CoV-2-inhibitor. … approaches to identify a possible
SARS-CoV-2-Inhibitor: i) Docking Consensus Approach (DCA) and ii) Common Hits Approach (CHA…
SARS-CoV-2-Inhibitor: i) Docking Consensus Approach (DCA) and ii) Common Hits Approach (CHA…
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
… Based on the phylogenetic similarity of the RdRp proteins of SARS-CoV and SARS-CoV-2,
the catalytic domain was selected for inhibitor docking of inhibitors against the SARS-CoV-2 …
the catalytic domain was selected for inhibitor docking of inhibitors against the SARS-CoV-2 …
[HTML][HTML] Unravelling Vitamin B12 as a potential inhibitor against SARS-CoV-2: A computational approach
… -2) is the etiological agent of Coronavirus … computational approach, we intend to identify
the probable inhibitory effect of all vitamins on the drug targets of COVID-19. The computational …
the probable inhibitory effect of all vitamins on the drug targets of COVID-19. The computational …
A computational approach for rational discovery of inhibitors for non-structural protein 1 of SARS-CoV-2
R Singh, VK Bhardwaj, P Das, R Purohit - Computers in biology and …, 2021 - Elsevier
… SARS-CoV-2 necessitates the use of computational tools … computational approach to select
and rank these analogues based on their capacity to effectively bind with Nsp1 of SARS-CoV…
and rank these analogues based on their capacity to effectively bind with Nsp1 of SARS-CoV…
Looking for SARS-coV-2 therapeutics through computational approaches
M Vincenzi, FA Mercurio… - Current Medicinal …, 2023 - ingentaconnect.com
… This work, supported by a computational approach, indicates that SARSCoV-2 develops
an efficacious immune escape strategy by letting its proteins take part in diverse immune and …
an efficacious immune escape strategy by letting its proteins take part in diverse immune and …
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