… The administration route has an impact on the infant exposure to the maternal drug. For
example… hope that the ConcePTION project will help generate new evidence on drug excretion in …

… Exposure of infants to isoniazid via breast milk after maternal drug intake of recommended
doses … A Physiologically-based pharmacokinetic (PBPK) Modelling approach to estimate drug …

… OR gravidity OR prenatal OR maternal OR gestation OR … However, there are studies that
assessed drugs used to treat … of the studies adjusted for maternal age, parity and smoking. …

… maternal medication during breastfeeding is lacking for most medications. This leads to
discontinuation of either breastfeeding or maternal … applied to predict drug-drug interactions and …

… from the Healthcare Cost and Utilization Project. We identified all records … drug use before
conception and starting treatment early in pregnancy are paramount to reducing maternal drug …

… drugs as well as stratified by drug class. The RR for spontaneous abortion was RR = 1.14,
95% CI 0.99–1.320, for preterm births RR = 0.93, 95% CI 0.72–1.21 and for major congenital …

… Weight-control interventions, including drug treatment, in … and lifestyle interventions
before conception. To improve … Interventions to reduce or prevent obesity before conception …

… A particular strength of this approach is that unique quantitative information on infant exposure
to maternal medicine can be generated in an early (drug-development) stage, ie, before …

… There were no known maternal deaths in our recent … conception or at an early stage in
the fetal gestation, but this represents a significant challenge to the operation of regular drug …

… was to evaluate common maternal medical conditions that … for an antipsychotic drug filled
between the conception date (… payments for their efforts on this project. Unrelated to this …