Gap junction channels formed by coexpressed connexin40 and connexin43

V Valiunas, J Gemel, PR Brink… - American Journal of …, 2001 - journals.physiology.org
… conductances could not be explained easily as homotypic Cx43 or Cx40 forms (18). These
… Cx40-Cx43 gap junction channels. However, they did not consider heterotypic Cx40-Cx43

Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation.

AP Moreno, JC Sáez, GI Fishman, DC Spray - Circulation research, 1994 - Am Heart Assoc
Connexin43 is the major gap protein in the heart and cardiovascular system. Single channel
recordings of human connexin43 gap junction … of heterotypic gap junctions formed by …

Role of connexin43-interacting proteins at gap junctions

BNG Giepmans - Cardiovascular Gap Junctions, 2006 - karger.com
… In conclusion, depending on cell type and context, adherens junction and gap junction
formation can be mutually affected, which seems to involve regulation of cell migration. While the …

[HTML][HTML] Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics

JL Solan, PD Lampe - Biochimica Et Biophysica Acta (BBA) …, 2018 - Elsevier
… (AJ) formation or through disruption of gap junction organization and channel … Cx43
phosphorylation on the gap junction life cycle, however, phosphorylation can also affect gap junction

Dual functions for connexins: Cx43 regulates growth independently of gap junction formation

C Moorby, M Patel - Experimental cell research, 2001 - Elsevier
… demonstrate that Cx43 can affect cell growth independently of gap junction formation. This …
lation between the action of Cx43 mutants Cx43– S255A, Cx43–S279A, and Cx43–S282A on …

Autoregulation of connexin43 gap junction formation by internally translated isoforms

JW Smyth, RM Shaw - Cell reports, 2013 - cell.com
Cx43. The 20 kDa isoform is sufficient to rescue this trafficking defect in trans, suggesting it as
a trafficking chaperone for Cx43… expression, increasing Cx43 gap junction size. The results …

Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
… Other than forming gap junctions, Connexin43 can also form hemichannels to release or
uptake small molecules from the environment or even mediate many physiological processes in …

The life cycle of a connexin: gap junction formation, removal, and degradation

DW Laird - Journal of bioenergetics and biomembranes, 1996 - Springer
… studies on isolated liver and heart gap junction membranes established that Cx32 and
Cx43 pass through the membrane four times forming two extracellular loops and a cytoplasmic …

Evidence for heteromeric gap junction channels formed from rat connexin43 and human connexin37

PR Brink, K Cronin, K Banach… - … of Physiology-Cell …, 1997 - journals.physiology.org
… A heteromeric gap junction channel is one that contains … form heteromers, we cotransfected
rat connexin43 (rCx43) and … to compare the observed gap junction channel activity with that …

Gap junction assembly: roles for the formation plaque and regulation by the C-terminus of connexin43

RG Johnson, JK Reynhout, EM TenBroek… - Molecular biology of …, 2012 - Am Soc Cell Biol
gap junction (GJ) assembly system with experimentally reaggregated cells, we analyzed “formation
labeling of sterols and immunolabeling for connexin43 (Cx43), we demonstrated that …