The involvement of the ERK-MAPK pathway in TGF-β1–mediated connexin43-gap junction formation in chondrocytes
Q Wang, C Zhou, D Zhang, J Zou, W Liu… - Connective Tissue …, 2019 - Taylor & Francis
… of chondrocytes communication by TGF-β1, is unknown. To clarify this point, we
investigated the effects of TGF-β1 on Cx43 expression and subsequent gap junction formation. …
investigated the effects of TGF-β1 on Cx43 expression and subsequent gap junction formation. …
TGF-β1 down-regulates connexin 43 expression and gap junction intercellular communication in rat hepatic stellate cells
MCC Lim, G Maubach, L Zhuo - European journal of cell biology, 2009 - Elsevier
… functional gap junctions composed of connexin 43 (Cx43) … human TGF-β1 (hTGF-β1), a
pro-fibrotic stimulus, decreases Cx43 … , hTGF-β1 increases the phosphorylation of Cx43 at serine …
pro-fibrotic stimulus, decreases Cx43 … , hTGF-β1 increases the phosphorylation of Cx43 at serine …
TGF‐β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling
Q Wang, C Zhou, X Li, L Cai, J Zou, D Zhang… - Cell …, 2019 - Wiley Online Library
… junction-boxed area in right vertical lane), we found that cells induced with TGF-β1 had
more Cx43 localized to cluster points along the cytoskeleton (F-actin) between the two cells. …
more Cx43 localized to cluster points along the cytoskeleton (F-actin) between the two cells. …
Expression and function of connexin 43 in human gingival wound healing and fibroblasts
R Tarzemany, G Jiang, H Larjava, L Häkkinen - PLoS One, 2015 - journals.plos.org
… proteins that form hemichannels and gap junctions (GJs) on the … analyzed, several MMPs
and TGF-β1, involved in regulation of … These responses involved MAPK, GSK3α/β and TGF-β …
and TGF-β1, involved in regulation of … These responses involved MAPK, GSK3α/β and TGF-β …
Differential regulation of connexin43 and connexin37 in endothelial cells by cell density, growth, and TGF-beta1
DM Larson, MJ Wrobleski, GD Sagar… - … of Physiology-Cell …, 1997 - journals.physiology.org
… several investigators to make gap junctions and to engage in … that homo- and heterocellular
gap junctions may contribute to … mRNAs for the gap junction proteins connexin43 (Cx43) (19) …
gap junctions may contribute to … mRNAs for the gap junction proteins connexin43 (Cx43) (19) …
TGF‐β1‐induced connexin43 promotes scar formation via the Erk/MMP‐1/collagen III pathway
X Li, L Guo, X Yang, J Wang, Y Hou… - Journal of Oral …, 2020 - Wiley Online Library
… is beneficial for the proliferation of keratinocytes and fibroblasts.16, 17 For the formation
of functional gap junctions during wound healing, TGF-β1 expression is increased, and …
of functional gap junctions during wound healing, TGF-β1 expression is increased, and …
TGF‐β1 up‐regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation
… Connexin43 (Cx43)-mediated gap junctional intercellular … We found that TGF-β1 treatment
up-regulated Cx43 expression … with TGF-β1 increased GJIC and the expression of the β …
up-regulated Cx43 expression … with TGF-β1 increased GJIC and the expression of the β …
TGF-β1 facilitates cell–cell communication in osteocytes via connexin43-and pannexin1-dependent gap junctions
W Liu, D Zhang, X Li, L Zheng, C Cui, Y Cui, J Sun… - Cell death …, 2019 - nature.com
… of TGF-β1 on cell–cell communication based on gap junctions … We first showed that
TGF-β1 positively affected the … that TGF-β1 increased expressions of connexin43 (Cx43) and …
TGF-β1 positively affected the … that TGF-β1 increased expressions of connexin43 (Cx43) and …
Connexin 43 hemichannels regulate the expression of wound healing-associated genes in human gingival fibroblasts
… (HCs) and gap junctions (GJs) on the … Cx43 assembled into distinct GJ and HC plaques in
GFBLs both in vivo and in vitro. Specific blockage of Cx43 HC function by TAT-Gap19, a Cx43 …
GFBLs both in vivo and in vitro. Specific blockage of Cx43 HC function by TAT-Gap19, a Cx43 …
Connexin43 plays diverse roles in co-ordinating cell migration and wound closure events
… The gap junction (GJ) protein connexin43 (Cx43) is one of the many molecules whose
expression has been found to be up-regulated in chronic wounds and as a result targeting it may …
expression has been found to be up-regulated in chronic wounds and as a result targeting it may …
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