… Although most expression studies indicate that pannexins do not form intercellular channels…
as compared with connexin hemichannels. The properties of pannexin channels, their roles …

… connexins, pannexins notably do not form endogenous gap junctions and act as bona fide
ion channels. The pannexins … gap junctions in all tissues and cell types is a difficult prospect. …

Connexins and integrins, the two structurally and functionally distinct families of transmembrane
proteins, have been shown to be inter-connected by various modes of cross-talk in cells, …

… , which is presumably mediated by connexin hemichannels that open as extracellular Ca
2+ is lowered. However, recent studies indicate that pannexin channels and P2X7 receptors, …

… of pannexins, a three-member family of proteins with similar secondary and tertiary structures
than connexins … the opening of hemichannels but not pannexin channels in cultured human …

… on the main significance of connexins and GJs to the physiology … The clinical importance of
connexins to the electrical activation … the prospect that αCT11 could have potential for clinical …

… A major component of these communication systems is composed of connexin (Cx)-containing …
Most of these products are released by the opening of Cxs and pannexin channels and …

… connexins in cancer cells in terms of specific connexin functions and propose that connexins
… the functions of connexins other than Cx43 without disrupting pannexin function will greatly …

… evidence of roles for connexin-formed channels in clinically relevant phenomena including
… , raising the prospect that this short peptide could have potential for clinical translation [84]. …

… about the function of connexin channels, mainly those formed by connexin-43, on immunity
… development of therapeutic tools to modulate connexin expression and/or channel activities …