… unselected cohort for phenotype, including consanguineous unions, had a statistically higher
diagnostic yield. Studies with a larger cohort … family history and consanguinity. The higher …

… consanguinity and autozygosity in the outbred population … genome wide F ROH in unselected
samples (standard deviation in … decades when more recent cohorts, composed of subjects …

… cohort (46.2%) is somewhat higher than the average diagnostic yield in unselected cohorts
… but is in keeping with yields reported in highly consanguineous populations.13, 14, 32, 33 …

… In these studies, almost the entire cohorts have GME ancestry, … population known to have
high inbreeding levels and/or … analysis in an European population, where consanguinity is not …

… populations in which a proportion of marriages are consanguineous, and for individuals …
are related through multiple loops of consanguinity (see under Populations With High Mean …

… population regarding the ACE gene in consanguineous … with children in the normal population.
Recessive genes do not … , next-generation sequencing, and cohort studies have identified …

… consanguinity-related counselling could have significant and broad health benefits in this
cohort and arguably in the larger Saudi population. … cohort (babies without CAs not selected as …

… Three cohorts were used for this analysis: one cohort to assess the hit rate between solo, …
illustration of the three cohort structures enrolled in this study. a Clinical testing cohort with the …

… consanguineous marriages than in the general population. This fact can be used to estimate
the number of such recessive genes in each individual of the population. … unselected series …

… were not selected … Consanguinity is a mixture of two words taken from Latin language; “con”
means similar and “sanguineus” means blood, it indicates an association between people …