… up tumor cell proliferation and metastasis and reduce the efficacy of antitumor factors and
therapies. … , activity, and phenotype during conventional therapies, as well as the association …

… , a tumor endothelium–enriched zinc-finger transcription factor, during tumor progression. …
with high ZEB1 expression in tumor endothelium had increased prevalence of metastases and …

… One of the main problem for conventional therapy is a low drug penetration into solid tumors
arising due to pathological structure of the tumor vasculature including highly tortuous with …

… Conventional therapies for colon cancer progression and metastasis include surgery, …
combination with conventional therapies may play an important role in limiting the progression of …

… To examine its clinical significance, we determined whether tumor cells surviving after
conventional treatments were enriched for cells bearing this CD44 + /CD24 −/low -MS signature. …

… therapies, they will not be discussed in this review. Instead, we will restrict our comments to
those therapies that are specifically designed to target tumor … Tumor progression is a major …

… CAFs as a mechanism of mutual adaptation to therapeutic pressure, thus underscoring
the need for targeting strategies aimed at sensitizing to conventional therapies (Fig. 2b). …

… cancer therapy, either to hormone-based or to conventional … role in the development and
progression of breast cancer [33]… be the first line endocrine therapy that greatly improves relapse…

… to therapy are regulated by inflammation, which either promotes or suppresses tumor progression,
… Chronic inflammation facilitates tumor progression and treatment resistance, whereas …

… adenocarcinoma was independent of the tumor differentiation, and low numbers of tumor-infiltrating
lymphocytes were a sign of high risk of tumor progression and fatal disease when …