COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging

GR Washko, G Parraga - European Respiratory Journal, 2018 - Eur Respiratory Soc
precision medicine” is the tailoring of medical treatment to individual patients, we define “precision
imaging… understanding of their specific imaging phenotypes and measurements. …

Noninvasive imaging biomarker identifies small airway damage in severe chronic obstructive pulmonary disease

DM Vasilescu, FJ Martinez, N Marchetti… - American journal of …, 2019 - atsjournals.org
… thoracic CT biomarker PRM fSAD correlates in COPD with both … the PRM Emph biomarker
correlates in COPD with enlarged … are clinically available CT biomarkers that can be used to …

Biomarkers in chronic obstructive pulmonary disease: the gateway to precision medicine

S Milne, DD Sin - Clinics in Chest Medicine, 2020 - chestmed.theclinics.com
… the characteristics of useful biomarkers while highlighting some of the challenges of
biomarker research in a complex disease, such as COPD. The move toward precision medicine …

Computed tomography–based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression

CJ Galbán, MK Han, JL Boes, KA Chughtai… - Nature medicine, 2012 - nature.com
… The motivation for the present study was to develop a robust CT-based imaging biomarker
that would allow for visualization and quantification of COPD phenotypes. Previously, we …

Quantitative Imaging Biomarkers in Precision Medicine

S Shaikh - Advances in Imaging: Step Towards Precision …, 2022 - Springer
chronic obstructive pulmonary disease (COPD) which are causes of mortality in the USA [3].
QIBA defines the more precise … airway in the COPD patients are important biomarkers for the …

[HTML][HTML] Early imaging biomarkers of lung cancer, COPD and coronary artery disease in the general population: rationale and design of the ImaLife (Imaging in …

C Xia, M Rook, GJ Pelgrim, G Sidorenkov… - European journal of …, 2020 - Springer
… State-of-the-art computed tomography (CT) allows early detection of lung cancer and
simultaneous evaluation of imaging biomarkers for the early stages of COPD, based on pulmonary …

Phenotyping COPD exacerbations using imaging and blood-based biomarkers

NM Alotaibi, V Chen, Z Hollander… - … of Chronic Obstructive …, 2018 - Taylor & Francis
… exacerbations of chronic obstructive pulmonary disease (AECOPD) are caused by a variety
of different etiologic agents. Our aim was to phenotype COPD exacerbations using imaging (…

Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: 3He MR Imaging and CT Parametric Response Maps

DPI Capaldi, N Zha, F Guo, D Pike, DG McCormack… - Radiology, 2016 - pubs.rsna.org
… (MR) imaging, provide other ways to quantify both functional and structural pulmonary
biomarkers of COPD (16–19). Hyperpolarized 3 He MR imaging apparent diffusion coefficients ( …

Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease

F Guo, D Capaldi, M Kirby, K Sheikh… - … of Medical Imaging, 2018 - spiedigitallibrary.org
… Pulmonary MRI and CT biomarker outputs for representative asthma and COPD patient. (a)
CT - He 3 MRI registration (lung lobes and segments not shown). (b) UTE dynamic proton …

Feasibility of deriving a novel imaging biomarker based on patient-specific lung elasticity for characterizing the degree of COPD in lung SBRT patients

K Hasse, J Neylon, Y Min, D O'Connell… - The British journal of …, 2019 - academic.oup.com
… In this article, we investigated lung tissue elasticity as a potential imaging biomarker for
COPD diagnosis using a set of 13 patients. Accuracy of the elasticity estimation was …