… study was to examine the impacts of unreported exacerbations on the change in HRQoL
at … stable COPD in China. It was hypothesised that patients with unreported exacerbations …

… the magnitude of the effect of exacerbations on patients with COPD. We also showed that
the frequency of exacerbations negatively impacted on the progression of disease severity as …

… the number of exacerbations and … COPD management should include drugs and other
interventions that reduce the frequency of exacerbations and minimize their negative impact …

… A group of patients with COPD exacerbation showed a moderate-to-large improvement in all
… that severe exacerbations of COPD have an independent negative prognostic impact, with …

… the importance of exacerbation prevention and the availability of new treatment options.
Severe COPD exacerbations are associated with high mortality, have negative impact on quality …

… patient’s COPD exacerbation is also associated with an impact in patient-related outcomes.
… the concept that COPD exacerbations have a negative effect on quality of life in patients with …

… Hospitalisations for exacerbations of COPD have an independent and negative … the
severity of COPD influences the impact of hospitalisations for COPD exacerbations on HRQoL. …

… , and negative effects on … impact on exacerbation frequency caused by the withdrawal of
ICS and found that ICS use did not alter the risk of moderate to severe COPD exacerbations. …

… of viral infections in COPD exacerbations (from 2001 to 2015) … the impact of seasonality on
COPD exacerbation frequency … minimise the negative impact of the current exacerbation. This …

… In view of the wide impact of COPD exacerbations, any therapy that prevents exacerbations
will … in rate of decline in FEV 1 ) was negative, tiotropium was associated with a reduction in …