… COPD exacerbations are responsible for the morbidity and mortality of this disease. The
relationship between exacerbations and patient-related clinical outcomes is not clearly …

… We have recently shown that COPD exacerbations may increase airway inflammation 5 and
that a significant proportion may not show complete symptomatic or physiological resolution. …

… COPD exacerbation and during treatment. We also analysed the possible independent
correlation between COPD exacerbation … stress/inflammatory markers in COPD exacerbation. …

… of COPD exacerbations may potentially impair lung tissues and lead to an accelerated rate of
decline in pulmonary function. … of frequency of COPD exacerbations on pulmonary function, …

… of acute exacerbations of COPD (AECOPD) on patients' health status beyond pulmonary
function. … Chronic obstructive pulmonary disease (COPD) is characterized by the onset of acute …

… A better understanding of the mechanisms underlying COPD exacerbations will help to
optimize use of the currently available and new interventions for preventing and treating …

… exacerbations of chronic obstructive pulmonary disease are associated with accelerated loss
of lung function, … determinants of COPD exacerbation in the Hokkaido COPD cohort study. …

… Finally, we show that exacerbations are preceded by lower functional status, increased
symptoms … , our findings also emphasize the importance of preventing COPD exacerbations and …

… We now know that COPD exacerbations are also associated … admission, but most COPD
exacerbations are treated in the … median exacerbation frequency is 2.5–3 exacerbations per …

… 32 During acute-on-chronic pulmonary hyperinflation of COPD exacerbations, the attendant
tachypnoea also results in reduced dynamic lung compliance (Cdyn) reflecting the effect of …