Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration

DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
cell and cytokine regulation in the spinal cord after SCI. Here we discuss the injury timeline
with a focus on cellular … corresponding changes that occur to the injury site. The majority of …

Inflammation and spinal cord injury: infiltrating leukocytes as determinants of injury and repair processes

A Trivedi, AD Olivas, LJ Noble-Haeusslein - Clinical neuroscience research, 2006 - Elsevier
… Here, we consider the complex cellular and molecular … In this review, we consider spinal
cord injury in the context of … well as leukocyte-mediated cell injury and repair processes. Lastly, …

Chemokine antagonist infusion attenuates cellular infiltration following spinal cord contusion injury in rat

RS Ghirnikar, YL Lee, LF Eng - Journal of Neuroscience …, 2000 - Wiley Online Library
… To reduce the inflammatory response after spinal cord injury, we have blocked the interaction
of chemokine receptors with their ligands using the vMIPII chemokine antagonist. Using a …

The pathophysiological role of acute inflammation after spinal cord injury

S Okada - Inflammation and regeneration, 2016 - Springer
… In the research field of SCI, the conventional evaluation of inflammatory cell infiltration has …
in the acute phase of injury when the most prominent cell infiltration is observed. We therefore …

Leukotriene B4 Release and Polymorphonuclear Cell Infiltration in Spinal Cord Injury

J Xu, CY Hsu, TH Liu, EL Hogan… - Journal of …, 1990 - Wiley Online Library
… traumatic polymorphonuclear cell infiltration determined by am yeloperoxidase assay. Results
from this study suggest that the source of leukotriene B4 in spinal cord injury is infiltrating

Embryonic stem cells promote motor recovery and affect inflammatory cell infiltration in spinal cord injured mice

D Bottai, D Cigognini, L Madaschi, R Adami… - Experimental …, 2010 - Elsevier
The purpose of this study was to determine the fate and the effects of undifferentiated embryonic
stem cells (ESCs) in mice after contusive lesion of the spinal cord (SCI). Reproducible …

Cellular inflammatory response after spinal cord injury in Sprague‐Dawley and Lewis rats

PG Popovich, P Wei, BT Stokes - Journal of comparative …, 1997 - Wiley Online Library
… -cell infiltration in the injured spinal cord of SD and LEW rats. … However, T-cell infiltrates in
injured LEW spinal cords did … Furthermore, T-cell margination in the SAS was qualitatively …

[HTML][HTML] Spinal cord injury scarring and inflammation: therapies targeting glial and inflammatory responses

MB Orr, JC Gensel - Neurotherapeutics, 2018 - Elsevier
… resident and infiltrating glial cells and associated therapies following traumatic spinal cord
injury. … Spinal cord injury creates cellular debris and releases intracellular proteins that act as …

Rats and mice exhibit distinct inflammatory reactions after spinal cord injury

JM Sroga, TB Jones, KA Kigerl… - Journal of …, 2003 - Wiley Online Library
… This is consistent with our previous comparisons of T-cell infiltration of the injured Lewis and
… , T-cell infiltration is always delayed relative to that in rats, dendritic cell infiltration is always …

Multiple channel bridges for spinal cord injury: cellular characterization of host response

Y Yang, LD Laporte, ML Zelivyanskaya… - … Engineering Part A, 2009 - liebertpub.com
cell infiltration, and also cellular responses. In the spinal cord, porous bridges support cellular
… the rate of cell infiltration, and the direction from which cells infiltrate. Initial designs of the …