Restoring function after spinal cord injury: towards clinical translation of experimental strategies

LM Ramer, MS Ramer, EJ Bradbury - The Lancet Neurology, 2014 - thelancet.com
… in spinal cord injury research … experimental treatments to the clinic, momentum and optimism
exist for the translation of candidate experimental treatments to clinical spinal cord injury. …

A systematic review of experimental strategies aimed at improving motor function after acute and chronic spinal cord injury

J Gomes-Osman, M Cortes, J Guest… - Journal of …, 2016 - liebertpub.com
While various approaches have been proposed in clinical trials aimed at improving motor
function after spinal cord injury in humans, there is still limited information regarding the scope, …

Experimental strategies to promote spinal cord regeneration—an integrative perspective

JM Schwab, K Brechtel, CA Mueller, V Failli… - Progress in …, 2006 - Elsevier
… damage phenomena after spinal cord injury (SCI) as well as the identification of inhibitory
and neurotrophic proteins have yielded a plethora of experimental therapeutic approaches. …

Current and future therapeutic strategies for functional repair of spinal cord injury

C Tohda, T Kuboyama - Pharmacology & therapeutics, 2011 - Elsevier
… development of experimental therapeutic strategies targeting … strategies have been tested
in clinical trials. However, fundamental treatment to regenerate safely the damaged spinal cord

Spinal cord injury repair research: a new combination treatment strategy

RV Krishnan, R Muthusamy… - International journal of …, 2001 - Taylor & Francis
… In this instance, our present experimental design of inductive lability could reasonably “distribute”
the overload to several grey matter segments and overcome this problem. …

[HTML][HTML] Current status of experimental cell replacement approaches to spinal cord injury

E Eftekharpour, S Karimi-Abdolrezaee… - Neurosurgical focus, 2008 - thejns.org
… Spinal cord injury involves an initial mechanical or primary injury followed by a series of
cellular and molecular secondary events resulting in progressive destruction of spinal cord tissue…

Cell-based transplantation strategies to promote plasticity following spinal cord injury

CA Ruff, JT Wilcox, MG Fehlings - Experimental neurology, 2012 - Elsevier
Cell transplantation therapy holds potential for repair and functional plasticity following
spinal cord injury (SCI). Stem and progenitor cells are capable of modifying the lesion …

Two experimental strategies to restore muscle mass in adult rats following spinal cord injury

RJL Murphy, EE Dupont-Versteegden… - … and Neural Repair, 1999 - journals.sagepub.com
Spinal cord injury decreases muscle mass and is associated with myofiber type trans formations
in skeletal muscles. The present study evaluated the potential of motor- assisted cycling …

Cell therapeutic strategies for spinal cord injury

P Zhou, J Guan, P Xu, J Zhao, C Zhang… - Advances in Wound …, 2019 - liebertpub.com
strategies. A comprehensive treatment of injury of spinal cord is the focus of the present
research… With the combination of different cell therapy strategies, future experiments will achieve …

Spinal cord injury: experimental animal models and relation to human therapy

SI Hodgetts, GW Plant, AR Harvey - The spinal cord, 2009 - Elsevier
… The majority of spinal cord injury (SCI) events occur in the 18… Increasing use is being made
of experimental animal models … behavioral outcomes with experimental strategies aimed at …