RNA sequencing screening of differentially expressed genes after spinal cord injury

Y Li, Y Chen, X Li, J Wu, JY Pan, RX Cai… - Neural Regeneration …, 2019 - journals.lww.com
sequencing technology (RNA sequencing) has provided a better method. In this study,
RNA sequencing … at different time points after spinal cord injury in rat models established by …

RNA-seq characterization of spinal cord injury transcriptome in acute/subacute phases: a resource for understanding the pathology at the systems level

K Chen, S Deng, H Lu, Y Zheng, G Yang, D Kim… - PloS one, 2013 - journals.plos.org
… In this study, we systematically characterized the transcriptome of spinal cord injury at acute
(2D) and subacute (7D) phases by RNA-Seq. With such an informative resource, we can …

RNA-seq analysis of microglia reveals time-dependent activation of specific genetic programs following spinal cord injury

HN Noristani, YN Gerber, JC Sabourin… - Frontiers in molecular …, 2017 - frontiersin.org
… competence to regrow following injury, although not spontaneously. Spinal cord injury (SCI) …
using RNA-sequencing. We demonstrate that activation of microglia is time-dependent post-…

Transcriptome profile of rat genes in injured spinal cord at different stages by RNA-sequencing

LL Shi, N Zhang, XM Xie, YJ Chen, R Wang, L Shen… - BMC genomics, 2017 - Springer
… Although the genes associated with damage and repair of spinal cord injury are still largely
unknown, the RNA-Seq analysis presented in this study will expand our understanding of the …

Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats

H Du, J Shi, M Wang, S An, X Guo, Z Wang - Journal of neuroinflammation, 2018 - Springer
… Using the Illumina HiSeq 4000 platform, we examined differentially expressed genes (DEGs)
in the rat dorsal horn by RNA sequencing (RNA-seq) between CCI and control groups. …

Expression of long non-coding RNAs in complete transection spinal cord injury: a transcriptomic analysis

L Ding, WJ Fu, HY Di, XM Zhang, YT Lei… - Neural Regeneration …, 2020 - journals.lww.com
cord injury (SCI), the expression signatures of lncRNAs were profiled using RNA sequencing
(RNA-seq) … A subset of these RNA-seq results was validated by quantitative real-time PCR. …

Single‐cell RNA sequencing for traumatic spinal cord injury

Y Cao, S Zhu, B Yu, C Yao - The FASEB Journal, 2022 - Wiley Online Library
… Single- cell RNA sequencing (scRNA- seq) has provided … the diversity of spinal cord
cell types. Specifically, scRNA- … in injured spinal cord at different stages by RNAsequencing. …

Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury

M Shu, X Xue, H Nie, X Wu, M Sun, L Qiao, X Li… - Science China Life …, 2022 - Springer
cord hold great potential for repair after spinal cord injury (… the NSCs source in the spinal
cord. However, the ependyma … SCI by single-cell RNA-sequencing (scRNA-seq). We identified …

Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury

H Wei, X Wu, J Withrow, RCD Duran, S Singh… - Cell reports, 2023 - cell.com
… spinal cord after injury and contribute to regeneration remains elusive. We perform single-cell
RNA sequencing of GFAP-expressing cells from sub-chronic spinal cord injury models and …

Combination of single-cell and bulk RNA seq reveals the immune infiltration landscape and targeted therapeutic drugs in spinal cord injury

Q Zhang, B Yu, Y Zhang, Y Tian, S Yang… - Frontiers in …, 2023 - frontiersin.org
… to further discover the consistency of immune cells with bulk RNA seq is our follow-up
research work. Second, although no obvious side effects were observed within 6 weeks, the mice …