Pathogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury
AP Amar, ML Levy - Neurosurgery, 1999 - journals.lww.com
… of acute spinal cord injury (SCI) support the concepts of primary and secondary injury, in
which the … events that promote progressive tissue damage and ischemia. Whereas the primary …
which the … events that promote progressive tissue damage and ischemia. Whereas the primary …
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade
C Oyinbo - Acta neurobiologiae experimentalis, 2011 - ane.pl
… Though both mechanisms are involved in the neurological dysfunction in SCI most research
however has focused on understanding the pathophysiology of the secondary damage and …
however has focused on understanding the pathophysiology of the secondary damage and …
Understanding secondary injury
RB Borgens, P Liu-Snyder - The Quarterly review of biology, 2012 - journals.uchicago.edu
… cord injury is due to the injury sustained by neuronal processes (axons), and not usually to
the loss or damage of … depending on the vertebral level of the spinal cord injury. High cervical …
the loss or damage of … depending on the vertebral level of the spinal cord injury. High cervical …
Function of microglia and macrophages in secondary damage after spinal cord injury
… By understanding how macrophages either promote or prevent secondary damage in spinal
cord inflammation, we may be able to deduce new approaches for mitigating the currently …
cord inflammation, we may be able to deduce new approaches for mitigating the currently …
Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
CH Tator, MG Fehlings - Journal of neurosurgery, 1991 - thejns.org
… nisms of damage to the spinal cord after acute spinal cord injury: the primary mechanical …
the importance of secondary injury mechanisms in patients with acute spinal cord injury. How…
the importance of secondary injury mechanisms in patients with acute spinal cord injury. How…
Advances in secondary spinal cord injury: role of apoptosis
J Lu, KWS Ashwell, P Waite - Spine, 2000 - journals.lww.com
… cord injury depends on the extent of secondary damage … the evidence that secondary spinal
cord injury involves the … as glutamatergic excitotoxicity, free radical damage, cytokines, and …
cord injury involves the … as glutamatergic excitotoxicity, free radical damage, cytokines, and …
Inflammogenesis of secondary spinal cord injury
MA Anwar, TS Al Shehabi, AH Eid - Frontiers in cellular neuroscience, 2016 - frontiersin.org
… injury along with sequential secondary damages emanating from multi-cascade of patho-mechanisms.
These secondary pathologic series of events lead to further damages to the SC. …
These secondary pathologic series of events lead to further damages to the SC. …
Acute spinal cord injury, part I: pathophysiologic mechanisms
RJ Dumont, DO Okonkwo, S Verma… - Clinical …, 2001 - journals.lww.com
… Spinal cord injury (SCI) is a devastating and common … cord injury may be divided into both
primary and secondary … However, secondary mechanisms of injury can exacerbate damage …
primary and secondary … However, secondary mechanisms of injury can exacerbate damage …
Update on the pathophysiology and pathology of acute spinal cord injury
CH Tator - Brain pathology, 1995 - Wiley Online Library
… and experimental studies that the spinal cord suffers both primary and secondary damage
after acute spinal cord injury. The pathophysiology of secondary injury involves a multitude of …
after acute spinal cord injury. The pathophysiology of secondary injury involves a multitude of …
Interactions of primary insult biomechanics and secondary cascades in spinal cord injury: implications for therapy
MB Orr, JC Gensel - Neural Regeneration Research, 2017 - journals.lww.com
… serve protective and reparative roles but also exacerbate damage and contribute to secondary
injury. The mediators of this secondary injury after SCI have been reviewed extensively (…
injury. The mediators of this secondary injury after SCI have been reviewed extensively (…
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