[HTML][HTML] Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response
Y Hou, J Luan, T Huang, T Deng, X Li, Z Xiao… - Journal of …, 2021 - Springer
… ) is a hydrophilic bile acid derivative, which has been … of TUDCA on spinal cord injury (SCI)
have not been fully elucidated. This study aims to investigate the protective effects of TUDCA …
have not been fully elucidated. This study aims to investigate the protective effects of TUDCA …
Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats
A Çolak, B Kelten, A Sağmanligil, O Akdemir… - Journal of Clinical …, 2008 - Elsevier
… spinal cord injury (SCI) has led to new and innovative apoptosis-based therapies for patients
with an SCI. Tauroursodeoxycholic acid (TUDCA) is a biliary acid … efficacy of TUDCA in an …
with an SCI. Tauroursodeoxycholic acid (TUDCA) is a biliary acid … efficacy of TUDCA in an …
Injectable hydrogel containing tauroursodeoxycholic acid for anti-neuroinflammatory therapy after spinal cord injury in rats
… containing tauroursodeoxycholic acid (TUDCA) in a spinal cord injury (SCI) model. To this
end, TUDCA-hydrogel (TC gel) is created by immersing the synthesized hydrogel in a TUDCA …
end, TUDCA-hydrogel (TC gel) is created by immersing the synthesized hydrogel in a TUDCA …
… of tauroursodeoxycholic acid–inducing M2‐phenotype macrophages promotes an anti‐neuroinflammatory effect and functional recovery after spinal cord injury in rats
… Schematic procedures of the transplantation therapy of tauroursodeoxycholic acid (TUDCA)–induced
M2-phenotype macrophages in the contusion spinal cord injury (SCI) rat model in …
M2-phenotype macrophages in the contusion spinal cord injury (SCI) rat model in …
[HTML][HTML] Tauroursodeoxycholic acid reduces neuroinflammation but does not support long term functional recovery of rats with spinal cord injury
S Wu, C García-Rama, L Romero-Ramírez… - Biomedicines, 2022 - mdpi.com
… The bile acid tauroursodeoxycholic acid (TUDCA) … of spinal cord injury (SCI). Since cell
death of injected bmSC limits the efficacy of this treatment, the cytoprotective effect of TUDCA …
death of injected bmSC limits the efficacy of this treatment, the cytoprotective effect of TUDCA …
[HTML][HTML] Mechanism of tauroursodeoxycholic acid-mediated neuronal protection after acute spinal cord injury through AKT signaling pathway in rats
Y Dong, S Yang, B Fu, F Liu, S Zhou… - … Journal Of Clinical …, 2020 - ncbi.nlm.nih.gov
… tauroursodeoxycholic acid-(TUDCA) mediated neuronal protection after acute spinal cord
injury … group (ASCI rats), TUDCA group (ASCI rats received TUDCA treatment), MK2206 group …
injury … group (ASCI rats), TUDCA group (ASCI rats received TUDCA treatment), MK2206 group …
[PDF][PDF] Protective effect of tauroursodeoxycholic acid on the autophagy of nerve cells in rats with acute spinal cord injury.
L Miao, Y Dong, FB Zhou, YL Chang… - European Review for …, 2018 - europeanreview.org
… TUDCA administration, caspase-3 expression was lower than that of the control group, …
after TUDCA administration. Therefore, we suggest that during early spinal cord injury, TUDCA …
after TUDCA administration. Therefore, we suggest that during early spinal cord injury, TUDCA …
Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene
Z Zhang, J Chen, F Chen, D Yu, R Li, C Lv… - Cell Stress and …, 2018 - Springer
… bile acid and recognized endoplasmic reticulum (ER) stress inhibitor, tauroursodeoxycholic
acid (TUDCA) … damage by inhibiting apoptosis in the early treatment of spinal cord injury. …
acid (TUDCA) … damage by inhibiting apoptosis in the early treatment of spinal cord injury. …
[HTML][HTML] Neuroprotective effects and impact on caspase-12 expression of tauroursodeoxycholic acid after acute spinal cord injury in rats
Y Dong, L Miao, L Hei, L Lin, H Ding - International journal of …, 2015 - ncbi.nlm.nih.gov
… effects of tauroursodeoxycholic acid (TUDCA) on nerve function after acute spinal cord injury
(… Methods: We used a modified Allen’s weight-drop trauma method to establish a rat acute …
(… Methods: We used a modified Allen’s weight-drop trauma method to establish a rat acute …
Application of tauroursodeoxycholic acid for treatment of neurological and non-neurological diseases: is there a potential for treating traumatic brain injury?
KR Gronbeck, CMP Rodrigues, J Mahmoudi… - Neurocritical care, 2016 - Springer
… potential of tauroursodeoxycholic acid (TUDCA) for neuroprotection in traumatic brain injury
(… systemic effects of TUDCA, and the potential therapeutic application of TUDCA. Preclinical …
(… systemic effects of TUDCA, and the potential therapeutic application of TUDCA. Preclinical …
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